89796-20-3

Upstream product

• 109-73-9 N-butylamine 
• 513-31-5 2-bromoallyl bromide 
• 6943-51-7 2-bromoallylamine 
• 123-72-8 butyraldehyde 

Downstream Products

• 39536-61-3 N-butylpentylamine 
• 74-86-2 acetylene 
• 44768-33-4 butyl(prop-2-ynyl)amine 
• 4482-17-1 1,4-diphenyl-but-2-yne-1,4-diol 
• 2403-22-7 N-Benzyl-N-butylamine 
• 1186610-94-5 2-{(N-(2-bromoprop-2-en-1-yl)-N-butylamino)methyl}-6-(methoxycarbonyl)-1-tosylindole 
• 1186610-92-3 2-{(N-(2-bromoprop-2-en-1-yl)-N-butylamino)methyl}-1-tosyl-6-(trifluoromethyl)indole 
• 1186610-90-1 2-{(N-(2-bromoprop-2-en-1-yl)-N-butylamino)methyl}-5-methyl-1-tosylindole 
• 1186610-85-4 2-{(N-(2-bromoprop-2-en-1-yl)-N-butylamino)methyl}-1-tosyl-5-trifluoromethylindole 
• 1186610-87-6 2-{(N-(2-bromoprop-2-en-1-yl)-N-butylamino)methyl}-5-(methoxycarbonyl)-1-tosylindole 
• 1186610-83-2 2-[(N-(2-bromoprop-2-en-1-yl)-N-butylamino)methyl]-1-tosylindole 
• 1346240-85-4 1-butyl-4-methyl-2-phenyl-1H-pyrrole 

Relevant academic research and scientific papers

Switchable Copper-Catalyzed Cascade Synthesis of Thiazolidine-2-thiones and Thiazole-2(3 H)-thiones

A novel copper-catalyzed cascade synthesis of thiazolidine-2-thiones from N-(2-bromoallyl)amines and carbon disulfide has been developed. The procedure combines carbamodithioic acid formation and copper-catalyzed intramolecular S-vinylation in one sequence. By elevating the temperature, the one-pot reaction efficiently affords thiazole-2(3H)-thiones in moderate to good yields.

A simple and efficient protocol to 1,2,4-substituted pyrroles via a sonogashira coupling-acid-catalyzed cyclization

A facile and efficient protocol for the synthesis of 1,2,4-substituted pyrrole derivatives was developed. As a result of the ready availability of materials and the simple operation, this type of reaction should have potential utility in organic synthesis. Georg Thieme Verlag Stuttgart · New York.

Preparation and Reactivity of New β-Nitrogen-Functionalized Vinylic Organolithium Compounds from Secondary Aliphatic Allylamines

Two new types of β-nitrogen-functionalized vinylic organolithium compounds have been prepared from secondary aliphatic allylamines through the temporary silylation of the amino group.The monoanionic intermediates 4, stable at -80 deg C, are generated by a bromine-lithium exchange reaction and the dianionic derivatives 2, stable at room temperature, by a tin-lithium transmetalation reaction.Both types of organolithium compounds react with different electrophiles giving functionalized allylamines 7 and 10-27.Moreover, dianionic derivatives 30,33 can be prepared directly by bromine-lithium exchange when the β-elimination reaction of hydrogen bromide in the lithium 2-bromoallylamide is structurally hindered.Additionally, a novel type of anionic 1,3-rearrangement of a trimethylsilyl group from nitrogen to carbon is described.