898-10-2Relevant academic research and scientific papers
One pot direct synthesis of oxazolines, benzoxazoles, and oxadiazoles from carboxylic acids using the Deoxo-Fluor reagent
Kangani, Cyrous O.,Kelley, David E.,Day, Billy W.
, p. 6497 - 6499 (2006)
A one-pot, high yield direct synthesis of various 2-substituted oxazolines, benzoxazoles, and 2-oxadiazoles from carboxylic acids using Deoxo-Fluor reagent is described.
METHOD FOR MANUFACTURING BENZOXAZOLE COMPOUNDS
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Paragraph 0028; 0031-0032, (2017/04/28)
A method for manufacturing benzoxazole compounds is provided and has steps of: processing a reaction between o-aminophenol or a derivative thereof and an acyl chloride compound, so as to obtain a first product; and adding the first product into a solution of polyphosphoric acid to carry out a cyclization, so as to form a benzoxazole compound.
Eine einfache Methode zur Herstellung von Benzoxazolen
Seha, Zdenek,Weis, Claus D
, p. 413 - 419 (2007/10/02)
The preparation of benzoxazoles by a facile one-pot reaction is reported.The reaction of carboxylic acids with 2-chloro-N-methyl-Δ1-pyrrolinium chloride in an excess of N-methyl-2-pyrrolidone afforded carboxylic acid chlorides which were converted subsequently to their 2-hydroxyanilides by addition of 2-aminophenols.Cyclization of the 2-hydroxy-anilides at elevated temperatures furnished the benzoxazoles in high yield and purity.
