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Usage

Uses

Used in Electronics and Display Industries:
2,2′-bis-trifluoromethyl-biphenyl-4,4′-dicarboxylic acid is used as a key intermediate in the production of specialty polymers and materials. Its high thermal stability and unique chemical properties contribute to the development of electroluminescent materials and liquid crystals, which are essential components in electronic devices and display technologies.
Used in Pharmaceutical Applications:
2,2′-bis-trifluoromethyl-biphenyl-4,4′-dicarboxylic acid is utilized in the development of advanced materials for pharmaceutical applications. Its chemical structure and properties make it a promising candidate for the synthesis of new drug molecules, potentially leading to the creation of novel therapeutic agents.
Used in Agrochemical Applications:
2,2′-bis-trifluoromethyl-biphenyl-4,4′-dicarboxylic acid is also employed in the agrochemical industry, where it is used as a starting material for the synthesis of new agrochemical products. Its versatility in chemical reactions allows for the development of innovative compounds that can be used in crop protection and other agricultural applications.

Upstream product

• 341-58-2 2,2'-bis(trifluoromethyl)benzidine 
• 124-38-9 carbon dioxide 
• 327-74-2 4-cyano-2-trifluoromethylaniline 
• 161320-01-0 2,2’-bis(trifluoromethyl)-4,4’-biphenyldicarbonitrile 
• 161320-00-9 4-iodo-3-trifluoromethylbenzonitrile 
• 89762-10-7 dimethyl 2,2'-bis(trifluoromethyl)-4,4'-biphenyl dicarboxylate 

Relevant academic research and scientific papers

Dynamic Coordination Chemistry of Fluorinated Zr-MOFs: Synthetic Control and Reassembly/Disassembly Beyond de Novo Synthesis to Tune the Structure and Property

Known for excellent stability, porosity and functionality, the high-valent Zr4+ metal–organic frameworks (Zr-MOFs) still meets synthetic challenge in modulating the strength of Zr-Ocarboxylate linkage. Herein we explore the unusual coordination dynamics of fluorinated Zr-MOFs by designing two trifluoromethyl modified ligands with distinct geometry preference to form a family of thermodynamic and kinetic products. The low-connecting kinetic Zr-MOFs possess substitutable coordination sites to endow Zr6-cluster with extra dynamic behaviors, thus opening a post-synthetic pathway to sequential reassembly/disassembly processes. Comprehensive factors, including ligand geometry, Zr6-cluster connectivity, acid modulator and reaction temperature/concentration, have been studied for controllable syntheses. The stability, hydrophobicity and gas adsorption/separation properties of obtained Zr-MOFs are explored. This work sheds light on the understanding of the dynamic coordination chemistry of Zr-MOFs beyond strong Zr?O bond, which poses a versatile platform for modification and functionalization of Zr-MOFs.

Highly Chemically Stable MOFs with Trifluoromethyl Groups: Effect of Position of Trifluoromethyl Groups on Chemical Stability

Metal-organic frameworks (MOFs) are a class of advanced porous crystalline materials. However, numerous MOFs have poor chemical stability, significantly restricting their industrial application. The introduction of trifluoromethyl groups around clusters o

Tunability of fluorescent metal-organic frameworks through dynamic spacer installation with multivariate fluorophores

Through dynamic spacer installation, five fluorescent metal-organic frameworks (MOFs) have been constructed based on a proto-MOF LIFM-28 and multivariate ligands as fluorophores. The emissions are tunable via insertion of fluorescent ligands, demonstrating a versatile approach for luminescence tuning by virtue of dynamic spacer installation using swing-role MOFs.

Preparation method for 2,2'-bis(trifluoromethyl)-4,4'-biphenyldicarbonyl chloride

The invention discloses a preparation method for 2,2'-bis(trifluoromethyl)-4,4'-biphenyldicarbonyl chloride. The preparation method comprises the following concrete steps: a, with 2,2'-bis(trifluoromethyl)-4,4'-diaminobiphenyl as a starting material, successively carrying out a diazotization reaction and a bromination reaction so as to obtain 2,2'-bis(trifluoromethyl)-4,4'-dibromobiphenyl; b, subjecting 2,2'-bis(trifluoromethyl)-4,4'-dibromobiphenyl to a Grignard reaction/substitution reaction at first and then to a reaction with carbon dioxide so as to obtain 2,2'-bis(trifluoromethyl)-4,4'-biphenyldicarboxylic acid; and c, subjecting 2,2'-bis(trifluoromethyl)-4,4'-biphenyldicarboxylic acid to chlorination so as to obtain 2,2'-bis(trifluoromethyl)-4,4'-biphenyldicarbonyl chloride. The method of the invention has the advantages of short synthesis route, low production cost, and in particular, high reaction yield, no need for highly toxic substances, high safety and suitability for industrial large-scale production.

Precise Modulation of the Breathing Behavior and Pore Surface in Zr-MOFs by Reversible Post-Synthetic Variable-Spacer Installation to Fine-Tune the Expansion Magnitude and Sorption Properties

To combine flexibility and modifiability towards a more controllable complexity of MOFs, a post-synthetic variable-spacer installation (PVSI) strategy is used to implement kinetic installation/ uninstallation of secondary ligands into/from a robust yet flexible proto-Zr-MOF. This PVSI process features precise positioning of spacers with different length, size, number, and functionality, enabling accurate fixation of successive breathing stages and fine-tuning of pore surface. It shows unprecedented synthetic tailorability to create complicated MOFs in a predictable way for property modification, for example, CO2and R22 adsorption/separation, thermal/chemical stability, and extended breathing behavior.

Flexible Zirconium Metal-Organic Frameworks as Bioinspired Switchable Catalysts

Flexible metal–organic frameworks (MOFs) are highly desirable in host–guest chemistry owing to their almost unlimited structural/functional diversities and stimuli-responsive pore architectures. Herein, we designed a flexible Zr-MOF system, namely PCN-700 series, for the realization of switchable catalysis in cycloaddition reactions of CO2with epoxides. Their breathing behaviors were studied by successive single-crystal X-ray diffraction analyses. The breathing amplitudes of the PCN-700 series were modulated through pre-functionalization of organic linkers and post-synthetic linker installation. Experiments and molecular simulations confirm that the catalytic activities of the PCN-700 series can be switched on and off upon reversible structural transformation, which is reminiscent of sophisticated biological systems such as allosteric enzymes.

Monomers containing bis(trifluoromethyl)biphenylene radicals

A class of polyesters comprising recurring units having certain bis(trifluoromethyl)biphenylene radicals is disclosed. The polyesters exhibit favorable solubility properties in certain organic solvents so as to facilitate the production of the polyesters via polycondensation methods to film- and fiber-forming molecular weights. Monomeric compounds comprising a bis(trifluoromethyl)biphenylene radical and useful for the production of the polyesters are also disclosed.