898045-00-6Relevant articles and documents
Synthesis of tyrosinase inhibitory kojic acid derivative
Lee, Yong Sup,Park, Jang Hyun,Kim, Min Hwan,Seo, Seon Hee,Kim, Hyoung Ja
, p. 111 - 114 (2006)
Kojic acid derivative 2 was synthesized by joining two pyrone rings through an ethylene linkage by Horner-Emmons reaction of phosphonate 6 with aldehyde 7. The intermediates 6 and 7 were derived from kojic acid. The tyrosinase inhibitory activity of 2 was
NOVEL KOJIC ACID CONJUGATED COMPOUNDS AND THEIR BIOLOGICAL APPLICATIONS
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Paragraph 0067; 0073-0074, (2016/10/10)
The present invention relates to a novel kojic acid conjugated compound conjugated by a click reaction of kojic acid and an antioxidant derivative, an antioxidant dietary supplement comprising the same, and a composition for external application on skin h
Synthesis of kojic acid-derived copper-chelating apoptosis inducing agents
Chen, Yu-Hua,Lu, Pei-Jung,Hulme, Christopher,Shaw, Arthur Y.
, p. 995 - 1003 (2013/04/24)
Three classes of kojic acid derivatives were synthesized and examined for their antiproliferative activity against HeLa cells. Both 8b and 11 co-treated with copper ion exhibited synergistic effect on the HeLa cell growth inhibition with GI50 v