898045-01-7Relevant academic research and scientific papers
D-AMINO ACID OXIDASE INHIBITORS AND THERAPEUTIC USES THEREOF
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, (2019/04/29)
The present invention relates to compounds of Formula (I): or a pharmaceutically acceptable salt thereof, wherein: each of A, B, C, D, and E, independently, is C, N, N—H, O, S, or absent is a single bond or a double bond; each of X, Y, and Z, independentl
Synthesis of kojic acid-derived copper-chelating apoptosis inducing agents
Chen, Yu-Hua,Lu, Pei-Jung,Hulme, Christopher,Shaw, Arthur Y.
, p. 995 - 1003 (2013/04/24)
Three classes of kojic acid derivatives were synthesized and examined for their antiproliferative activity against HeLa cells. Both 8b and 11 co-treated with copper ion exhibited synergistic effect on the HeLa cell growth inhibition with GI50 v
Synthesis of kojic acid derivatives as secondary binding site probes of d-amino acid oxidase
Raje, Mithun,Hin, Niyada,Duvall, Bridget,Ferraris, Dana V.,Berry, James F.,Thomas, Ajit G.,Alt, Jesse,Rojas, Camilo,Slusher, Barbara S.,Tsukamoto, Takashi
supporting information, p. 3910 - 3913 (2013/07/25)
A series of kojic acid (5-hydroxy-2-hydroxymethyl-4H-pyran-4-one) derivatives were synthesized and tested for their ability to inhibit d-amino acid oxidase (DAAO). Various substituents were incorporated into kojic acid at its 2-hydroxymethyl group. These
Synthesis of tyrosinase inhibitory kojic acid derivative
Lee, Yong Sup,Park, Jang Hyun,Kim, Min Hwan,Seo, Seon Hee,Kim, Hyoung Ja
, p. 111 - 114 (2007/10/03)
Kojic acid derivative 2 was synthesized by joining two pyrone rings through an ethylene linkage by Horner-Emmons reaction of phosphonate 6 with aldehyde 7. The intermediates 6 and 7 were derived from kojic acid. The tyrosinase inhibitory activity of 2 was
