89808-74-2

Basic information

• Product Name: 5-(2-CHLOROPHENYL)OXAZOLE
• Synonyms: 5-(2-CHLOROPHENYL)OXAZOLE;5-(2-CHLOROPHENYL)-1,3-OXAZOLE;5-(2-Chlorophenyl)-1,3-oxazole 98%;5-(2-Chlorophenyl)-1,3-oxazole98%
• CAS NO: 89808-74-2
• Molecular Formula: C₉H₆ClNO
• Molecular Weight: 179.6
• Product Categories: Halides;Phenyls & Phenyl-Het;Oxazole&Isoxazole;Phenyls & Phenyl-Het
• Mol File: 89808-74-2.mol
• Article Data: 3

Chemical Properties

• Melting Point: 33-35
• Boiling Point: 274.7 °C at 760 mmHg
• Flash Point: 120 °C
• Appearance: /
• Density: 1.258g/cm³
• PKA: 0.17±0.10(Predicted)
• CAS DataBase Reference: 5-(2-CHLOROPHENYL)OXAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(2-CHLOROPHENYL)OXAZOLE(89808-74-2)
• EPA Substance Registry System: 5-(2-CHLOROPHENYL)OXAZOLE(89808-74-2)

Safety Data

• Hazard Codes: Xi,T
• Statements: 25
• Safety Statements: 45
• Hazardous Substances Data: 89808-74-2(Hazardous Substances Data)

Usage

General Description

5-(2-Chlorophenyl)oxazole, also known as 2-Chloro-5-phenyloxazole or 2-Chloro-5-phenyl-1,3-oxazole, is a chemical compound with the molecular formula C9H6ClNO. It is a heterocyclic aromatic organic compound that contains both oxygen and nitrogen atoms in a five-membered ring. 5-(2-CHLOROPHENYL)OXAZOLE is commonly used as a building block in the synthesis of various pharmaceuticals, agrochemicals, and other organic compounds. It is also used as a reagent in organic chemistry and as a fluorescent probe in biological studies. 5-(2-Chlorophenyl)oxazole has applications in the preparation of various types of heterocyclic compounds and has potential uses in the pharmaceutical and chemical industries due to its versatile reactivity and utility in organic synthesis.

Upstream product

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Downstream Products

• 1227747-49-0 C₁₉H₁₃ClN₂OS 

Relevant articles and documents

4-PHENYL-N-(PHENYL)THIAZOL-2-AMINE DERIVATIVES AND RELATED COMPOUNDS AS ARYL HYDROCARBON RECEPTOR (AHR) AGONISTS FOR THE TREATMENT OF E.G. ANGIOGENESIS IMPLICATED OR INFLAMMATORY DISORDERS

4-phenyl-N-(phenyl)thiazol-2-amine and 4-(pyridin-3-yl)-N-( phenyl) thiazol-2-amine derivatives and the corresponding thiadiazole, thiophene, oxazole, oxadiazole, imidazole and triazole derivatives and related compounds as aryl hydrocarbon receptor (AHR) agonists for the treatment of angiogenesis implicated disorders, such as e.g. retinopathy, psoriasis, rheumatoid arthritis, obesity and cancer, or inflammatory disorders.

Tandem cycloaddition-decarboxylation of α-keto acid and isocyanide under oxidant-free conditions towards monosubstituted oxazoles

An efficient method, tandem [3 + 2] cycloaddition-decarboxylation of α-keto acid and isocyanide promoted by copper salt, has been developed. Under oxidant-free conditions, a series monosubstituted oxazoles have been constructed. Different from the traditional application of α-oxo acids as acyl surrogates, the elegant approach herein ingeniously avoids consuming excess oxidants.