898281-47-5

Upstream product

• 543712-83-0 5-bromo-2-chloro-N-(5-cyclopropyl-1H-pyrazol-3-yl)pyrimidin-4-amine 
• 19293-58-4 (4-aminomethylphenyl)dimethylamine 

Relevant academic research and scientific papers

Methods of Using IGFIR and ABL Kinase Modulators

The invention provides methods of treating cancer with a compound which inhibits kinases, more specifically IGF1R and Abl, in combination with treatments(s) selected from surgery, radiation, monoclonal antibody, bone marrow or peripheral blood stem cell t

Pyrimidine Derivatives As Kinase Modulators and Method of Use

The invention provides compounds and methods for inhibition of kinases, more specifically IGF 1 R kinases. The invention also provides compounds and methods for inhibition of wildtype Abl. The invention provides compounds for modulating protein kinase enz