898530-76-2

Upstream product

• 1745-07-9 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline 
• 121580-34-5 2,2,2-trifluoro-1-(1,2,3,4-tetrahydro-6,7-dimethoxyisoquinolin-2(1H)-yl)ethanone 
• 120-20-7 2-(3,4-dimethoxyphenyl)-ethylamine 
• 898530-60-4 5,8-dibromo-2-(o-nitrobenzenesulfonyl)-1,2,3,4-tetrahydro-6,7-dimethoxy-1-hydroxyisoquinoline 
• 898530-59-1 5,8-dibromo-3,4-dihydro-6,7-dimethoxyisoquinoline 
• 898530-62-6 N-(o-nitrobenzenesulfonyl)-4-hydroxymethyl-5-bromo-6,7-dimethoxyindoline 
• 898530-61-5 {2-[2-(o-nitrobenzenesulfonyl)aminoethyl]-3,6-dibromo-4,5-dimethoxyphenyl}methanol 
• 898530-74-0 1-(5,8-dibromo-1,2,3,4-tetrahydro-6,7-dimethoxyisoquinolin-2(1H)-yl)-2,2,2-trifluoroethanone 
• 898530-75-1 5,8-dibromo-1,2,3,4-tetrahydro-6,7-dimethoxyisoquinoline 

Downstream Products

• 898530-69-3 (-)-methyl 3-[(8S)-4-benzyloxy-6-(5-benzyloxy-6-methoxy-1H-indol-2-yl)carbonyl-6,7,8,9-tetrahydro-8-methanesulfonyloxy-3H-pyrrolo[3,2-f]quinoline-2-yl]carbonyl-4-hydroxy-5-methoxy-1,2-dihydro-3H-pyrrolo[3,2-e]indole-7-thiocarboxylate 
• 898530-78-4 benzyl 3-(9H-fluoren-9-yl)methoxycarbonyl-4,5-dimethoxy-6-benzyloxycarbonyl-1,2-dihydro-3H-pyrrolo[3,2-e]indole-7-carboxylate 
• 898530-65-9 benzyl 3-(o-nitrobenzenesulfonyl)-4,5-dimethoxy-6-benzyloxycarbonyl-1,2-dihydro-3H-pyrrolo[3,2-e]indole-7-carboxylate 
• 898530-77-3 benzyl 4,5-dimethoxy-6-benzyloxycarbonyl-1,2-dihydro-3H-pyrrolo[3,2-e]indole-7-carboxylate 
• 898530-64-8 (Z)-3-[N-(o-nitrobenzenesulfonyl)-5-bromo-6,7-dimethoxyindolin-4-yl]-2-benzyloxycarbonylaminoacrylic acid methyl ester 

Relevant academic research and scientific papers

Total synthesis of (+)-yatakemycin

A convergent total synthesis of (+)-yatakemycin was accomplished in a 20-step sequence in an overall yield of 13%. The synthesis features the regioselective ring opening of (S)-epichlorohydrin with 2,6-dibromophenyllithium species, the mild copper-mediated aryl amination utilizing the combination of CuI and CsOAc, and the efficient deprotection of benzyl groups of aryl benzyl ether with BCl3 in the presence of pentamethylbenzene. Copyright