121580-34-5Relevant articles and documents
Total synthesis of (+)-yatakemycin
Okano, Kentaro,Tokuyama, Hidetoshi,Fukuyama, Tohru
, p. 7136 - 7137 (2007/10/03)
A convergent total synthesis of (+)-yatakemycin was accomplished in a 20-step sequence in an overall yield of 13%. The synthesis features the regioselective ring opening of (S)-epichlorohydrin with 2,6-dibromophenyllithium species, the mild copper-mediated aryl amination utilizing the combination of CuI and CsOAc, and the efficient deprotection of benzyl groups of aryl benzyl ether with BCl3 in the presence of pentamethylbenzene. Copyright