898531-99-2

Upstream product

• 1001429-79-3 (2S,3S,4R)-1,3,4-tris-(tert-butyldimethylsilanyloxy)-2-(N-tert-butoxycarbonyl)aminooctadecane 
• 1001429-69-1 (1'S,2'S,3'R)-[2,3-bis-(tert-butyldimethylsilanyloxy)-1-(hydroxymethyl)heptadecyl]carbamic acid tert-butyl ester 
• 1260236-37-0 (2S,3S,4R)-2-[(N-tert-butoxycarbonyl)amino]-3,4-di-tert-butyldimethylsilyloxy-1-O-(2,3,4,6-tetrakis-O-trimethylsilyl-α-D-galactopyranosyl)octadecane 
• 1260236-38-1 (2S,3S,4R)-2-[(N-tert-butoxycarbonyl)amino]-3,4-di-tert-butyldimethylsilyloxy-1-O-(2,3,4-tri-O-trimethylsilyl-α-D-galactopyranosyl)octadecane 
• 1260236-39-2 (2S,3S,4R)-2-[(N-tert-butoxycarbonyl)amino]-3,4-di-tert-butyldimethylsilyloxy-1-O-(6-deoxy-6-azido-2,3,4-tri-O-trimethylsilyl-α-D-galactopyranosyl)octadecane 
• 1260236-35-8 (2S,3S,4R)-2-[(N-tert-butoxycarbonyl)amino]-1-O-(6-deoxy-6-azido-α-Dgalactopyranosyl)octadecane-3,4-diol 
• 1260236-36-9 (2S,3S,4R)-2-amino-1-O-(6-deoxy-6-azido-α-D-galactopyranosyl)octadecane-3,4-diol 
• 75-36-5 acetyl chloride 
• 554-62-1 D-ribo-phytosphingosine 
• 506-37-6 Nervonic acid 
• 145411-43-4 (Z)-tetracos-15-enoyl chloride 
• 175696-50-1 tert-butyl [(2S,3S,4R)-1,3,4-trihydroxyoctadecan-2-yl]carbamate 
• 352432-47-4 2,3,4,6-tetra-O-tetramethylsilyl-α-D-galactopyranosyl iodide 
• 1769-00-2 1,2,3,4,6-penta-O-trimethylsilyl-α-D-galactose 

Relevant academic research and scientific papers

A comparison of benzyl and 2-naphthylmethyl ethers as permanent hydroxyl protecting groups in the synthesis of α-galactoglycosphingolipids KRN7000 and PBS-57

Due to the interest in the biological properties of marine derived α-galactoglycosphingolipids (α-GalGSLs), a lot of work has focused on the development of their synthesis. Here we conducted the direct comparison of benzyl and 2-naphthylmethyl (Nap) ether

Synthesis of a versatile building block for the preparation of 6-N-derivatized α-galactosyl ceramides: Rapid access to biologically active glycolipids

A concise route to the 6-azido-6-deoxy-α-galactosyl-phytosphingosine derivative 9 is reported. Orthogonal protection of the two amino groups allows elaboration of 9 into a range of 6-N-derivatized α-galactosyl ceramides by late-stage introduction of the a

MODIFIED -GALACTOSYL CERAMIDES FOR STAINING AND STIMULATING NATURAL KILLER T CELLS

Modified glycolipid compounds are provided. Also disclosed are methods for activating an NKT cell, methods of stimulating an immune response in a subject, and methods suitable for labeling NKT cells.