898534-13-9Relevant academic research and scientific papers
Convergent synthesis of the quinolone substructure of BILN 2061 via carbonylative sonogashira coupling/cyclization
Haddad, Nizar,Tan, Jonathan,Farina, Vittorio
, p. 5031 - 5034 (2006)
A convergent synthesis of quinolone 2 (key substructure of the protease inhibitor BILN 2061) was developed via palladium-catalyzed carbonylation of 2-iodo-5-methoxy-aniline (4) with thiazolylacetylene 5.
