898541-20-3Relevant articles and documents
Perchloric acid impregnated on silica gel (HClO4/SiO 2): A versatile catalyst for Michael addition of thiols to the electron-deficient alkenes
Khan, Abu T.,Ghosh, Subrata,Choudhury, Lokman H.
, p. 2226 - 2231 (2007/10/03)
Perchloric acid adsorbed on silica gel (HClO4X/SiO2) has been found to be a highly efficient and versatile catalyst for the Michael addition of thiols to a wide variety of conjugated alkenes such as α,α-unsaturated ketones, carboxylic esters, nitriles, amides and chalcones in dichloromethane or methanol at room temperature. The reactions are completed within 2-20 min in high yields. Some of the additional advantages are: no aqueous work-up is necessary, and the catalyst is also reusable. Moreover, the solid product can be obtained without chromatographic separation. Wiley-VCH Verlag GmbH & Co. KGaA, 2006.
Chiral 1,3-oxathiane from (+)-pulegone: Hexahydro-4,4,7-trimethyl-4H-1,3-benzoxathiin
Elie, Ernest L.,Lynch, Joseph E.,Kume, Fumitaka,Frye, Stephen V.
, p. 215 - 215 (2017/05/20)
-
ASYMMETRIC SYNTHESIS OF (R)-(+)-ETHYLMETHYL-n-PROPYLCARBINOL IN HIGH ENANTIOMERIC PURITY. A 1,3-OXATHIANE DERIVED FROM (+)-PULEGONE AS CHIRAL ADJUVANT
Eliel, Ernest L.,Lynch, Joseph E.,Kenan, William R. Jr.
, p. 2855 - 2858 (2007/10/02)
A chiral, conformationally locked 1,3-oxathiane has been prepared by 1,4-addition of benzyl mercaptan to (+)-pulegone followed by Na/NH3 reduction and condensation of the resulting hydroxythiol with paraformaldehyde.The utility of this chiral adjuvant is
