898542-52-4Relevant academic research and scientific papers
Isatin compounds as noncovalent SARS coronavirus 3C-like protease inhibitors
Zhou, Lu,Liu, Ying,Zhang, Weilin,Wei, Ping,Huang, Changkang,Pei, Jianfeng,Yuan, Yaxia,Lai, Luhua
, p. 3440 - 3443 (2007/10/03)
A series of isatin derivatives were synthesized and tested against SARS CoV 3C-like protease. Substitutions at the N-1 and C-5 positions were examined to elucidate the differences in substrate binding sites of the rhinovirus 3C protease and SARS CoV 3C-li
