898547-05-2

Upstream product

• 274-09-9 Methylenedioxybenzene 
• 898547-03-0 (3R,4S,5S)-5-(4-Benzyloxy-3-methoxy-phenyl)-3,4-dimethyl-dihydro-furan-2-one 
• 898547-00-7 (2S,3S)-3-(4-(benzyloxy)-3-methoxyphenyl)-3-((tert-butyldimethylsilyl)oxy)-2-methylpropan-1-ol 
• 898547-01-8 (((1S,2S)-1-(4-(benzyloxy)-3-methoxyphenyl)-2,3-dimethylbut-3-en-1-yl)oxy)(tert-butyl)dimethylsilane 
• 898547-02-9 (2R,3S,4S)-4-(4-(benzyloxy)-3-methoxyphenyl)-4-((tert-butyldimethylsilyl)oxy)-2,3-dimethylbutan-1-ol 
• 898546-99-1 (S)-4-benzyl-3-((2R,3S)-3-(4-(benzyloxy)-3-methoxyphenyl)-3-hydroxy-2-methylpropanoyl)oxazolidin-2-one 
• 2426-87-1 3-methoxy-4-(phenylmethoxy)benzaldehyde 

Relevant academic research and scientific papers

First enantioselective synthesis of (-)-talaumidin, a neurotrophic diaryltetrahydrofuran-type lignan

The first enantioselective total synthesis of a neurotrophic (-)-talaumidin (1) is described in 16 steps from 4-benzyloxy-3-methoxybenzaldehyde in ca. 10.7% overall yield, and thus has established the absolute configurations of the four stereogenic center