89863-73-0Relevant academic research and scientific papers
Trimethylsilyloxide-Catalysed Peterson Olefinations with 2,2-Bis(trimethylsilyl)-1,3-dithiane
Manvar, Atul,O'Shea, Donal F.
supporting information, p. 7259 - 7263 (2015/11/25)
The synthesis of the reagent 2,2-bis(trimethylsilyl)-1,3-dithiane was directly achieved in an excellent yield from 1,3-dithiane in one step. The bench-stable reagent can be utilized for Peterson olefinations using either TMSOK/Bu4NCl or fluorid
Fluorinated ketene dithioacetals; 1. Preparation and application to the synthesis of α-trifluoromethylthiocarboxylic S-esters and aldehyde derivatives
Muzard,Portella
, p. 965 - 968 (2007/10/02)
α-Trifluoromethylketene dithioacetals 3 were synthesized by Peterson reaction from trifluoromethyl ketones 1 and trimethylsilyl dithioacetals 2. Acid hydrolysis and reduction yield α-trifluoromethylthiocarboxylic S-esters 4 and α-trifluoromethyl dithioace
1,3-dithiolan-2-ylidenes their 1-oxides, pharmaceutical compositions, and methods of use thereof
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, (2008/06/13)
The invention relates to the use of ketenethioacetals of the formula STR1 in which R1 represents aryl or heteroaryl, R2 represents hydrogen, an optionally substituted hydrocarbon radical, heteroaryl, an acyl radical, a group of the formula --S(O)m --Ra, wherein m is 0, 1, or 2 and Ra is an optionally substituted hydrocarbon radical; or optionally functionally modified sulpho, A represents an optionally substituted bivalent aliphatic hydrocarbon radical and n is 0 or 1, and pharmaceutically acceptable salts of such compounds that contain a salt-forming group, for the treatment of liver diseases, respiratory tract diseases and vascular diseases pharmaceutical preparations containing compounds of the formula I and novel compounds of the formula I. The compounds have liver-protecting and immunomodulating properties.
