89868-13-3

Usage

Uses

Given the limited information available on 3-Chloro-6-phenyl-pyridazin-4-ol, its potential uses can only be inferred based on the general properties of pyridazine compounds and their derivatives. Here are some possible applications:
Used in Pharmaceutical Industry:
3-Chloro-6-phenyl-pyridazin-4-ol may be used as a pharmaceutical intermediate or a lead compound for the development of new drugs. Its unique structure and functional groups could potentially be exploited to target specific biological pathways or receptors, offering therapeutic benefits in various diseases.
Used in Chemical Reactions:
In the field of organic chemistry, 3-Chloro-6-phenyl-pyridazin-4-ol could serve as a reactant or a building block in the synthesis of more complex molecules. Its reactivity and functional groups may facilitate the formation of new chemical bonds or the creation of novel compounds with desired properties.
Used in Research and Development:
Due to the limited research on 3-Chloro-6-phenyl-pyridazin-4-ol, it may be used as a subject of study in academic or industrial research settings. Further investigation into its properties, reactivity, and potential applications could lead to new discoveries and innovations in the fields of chemistry, biology, and medicine.

InChI:InChI=1/C10H7ClN2O/c11-10-9(14)6-8(12-13-10)7-4-2-1-3-5-7/h1-6H,(H,12,14)

Upstream product

• 64942-62-7 3,4-dichloro-6-phenylpyridazine 
• 1011-46-7 6-phenyl-2,3,4,5-tetrahydropyridazin-3-one 
• 2051-95-8 succinylbenzene 
• 87769-64-0 4,5,-dihydro-6-phenyl-2-(phenylmethyl)-3(2H)-pyridazinone 

Downstream Products

• 89868-16-6 6-phenyl-4-pyridazol 
• 1449104-97-5 3-chloro-4-(4-methoxyphenoxy)-6-phenylpyridazine 
• 1449105-03-6 N-(4-bromophenyl)-2-[4-(4-methoxyphenoxy)-6-phenylpyridazin-3-ylamino]acetamide 
• 1449105-02-5 2-[4-(4-methoxyphenoxy)-6-phenylpyridazin-3-ylamino]acetic acid 
• 1449105-01-4 ethyl 2-[4-(4-methoxyphenoxy)-6-phenylpyridazin-3-ylamino]acetate 
• 1449105-00-3 4-bromo-N-[4-(4-methoxyphenoxy)-6-phenylpyridazin-3-yl]benzamide 
• 1449104-99-7 1-(4-bromophenyl)-3-[4-(4-methoxyphenoxy)-6-phenylpyridazin-3-yl]urea 
• 1449104-98-6 4-(4-methoxyphenoxy)-6-phenylpyridazin-3-amine 
• 886208-70-4 4-chloro-6-phenyl-3-(4-pyrimidin-2-yIpiperazin-1-yl)pyridazine 
• 886208-67-9 6-phenyl-3-(4-(pyrimidin-2-yl)piperazin-1-yl)pyridazin-4-ol 
• 89868-15-5 3-(dimethylamino)-6-phenyl-4-pyridazinol 

Relevant academic research and scientific papers

FORMULATIONS CONTAINING PYRIDAZINE COMPOUNDS

The invention relates to chemical compounds, compositions and methods of making and using the same. In particular, the invention provides selected pyridazine compounds of the formula I are independently hydrogen, hydroxyl, alkyl, alkenyl, alkynyl, alkylene, alkenylene, alkoxy, alkenyloxy, cycloalkyl, cycloalkenyl, cycloalkynyl, cycloalkoxy, aryl, aryloxy, arylalkoxy, aroyl, heteroaryl, heterocyclic, acyl, acyloxy, amino, imino, azido, thiol, thioalkyl, thioalkoxy, thioaryl, nitro, cyano, halo, sulfate, sulfenyl, sulfinyl, sulfonyl, sulfonate, sulfoxide, silyl, silyloxy, silylalkyl, silylthio, ═O, ═S, phosphonate, ureido, carboxyl, carbonyl, carbamoyl, or carboxamide; and X is optionally substituted pyrimidinyl or pyridazinyl, an isomer, a pharmaceutically acceptable salt, or derivative thereof. The invention additional relates to compositions comprising the compounds, and methods of using the compounds and compositions for modulation of cellular pathways, for treatment or prevention of inflammatory diseases, for research, drug screening, and therapeutic applications.

COMPOSITIONS AND TREATMENTS FOR DEMYELINATING DISEASES AND PAIN DISORDERS

The invention relates to compositions and methods for treating patients with Demyelinating Diseases and Conditions including Multiple Sclerosis, Spinal Cord Injury, Traumatic Brain Injury and Stroke. The compositions and methods may also be used for Stroke Rehabilitation and the treatment of pain disorders including Neuropathic Pain and Chemokine-Induced Pain. The compositions comprise one or more pyridazine compounds having a pyridazinyl radical pendant with an aryl or substituted aryl, a heteroaryl or substituted heteroaryl.

Development of a novel therapeutic suppressor of brain proinflammatory cytokine up-regulation that attenuates synaptic dysfunction and behavioral deficits

We report the development of a novel, aqueous-soluble, safe, small molecule, experimental therapeutic that suppresses injury-induced, proinflammatory cytokine increases in the brain, with resultant attenuation of synaptic protein biomarker loss and improvement in hippocampus-dependent behavioral deficits. A GMP production scheme for the active pharmaceutical ingredient, compound 17, is presented. The development and large-scale availability of this novel compound allow exploration of new, potentially disease-modifying, therapeutic approaches to CNS disorders.

COMPOSITIONS AND TREATMENTS USING PYRIDAZINE COMPOUNDS AND SECRETASES

The invention relates to compositions, conjugates and methods comprising pyridazine compounds and secretase inhibitors for modulation of cellular pathways (e.g., signal transduction pathways), for treatment or prevention of inflammatory diseases (e.g., Alzheimer's disease), for research, drug screening, and therapeutic applications.