87769-64-0 Usage
Description
2-Benzyl-6-phenyl-4,5-dihydropyridazin-3(2H)-one is a heterocyclic compound belonging to the class of dihydropyridazines. It features a six-membered ring with two nitrogen atoms and is known for its potential pharmacological and biological activities. This chemical has antioxidant, antifungal, and anticancer properties, positioning it as a promising candidate for drug development. Its unique structure and diverse biological activities make it a target for further research and potential applications in the pharmaceutical and medical fields.
Uses
Used in Pharmaceutical Industry:
2-Benzyl-6-phenyl-4,5-dihydropyridazin-3(2H)-one is used as a potential drug candidate for its antioxidant, antifungal, and anticancer properties. Its diverse biological activities make it a valuable target for the development of new medications to treat various diseases and conditions.
Used in Medical Research:
In the field of medical research, 2-benzyl-6-phenyl-4,5-dihydropyridazin-3(2H)-one serves as a subject of study for its potential applications in treating diseases. Its unique structure and pharmacological properties provide a foundation for exploring new therapeutic approaches and understanding the underlying mechanisms of its biological effects.
Check Digit Verification of cas no
The CAS Registry Mumber 87769-64-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,7,7,6 and 9 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 87769-64:
(7*8)+(6*7)+(5*7)+(4*6)+(3*9)+(2*6)+(1*4)=200
200 % 10 = 0
So 87769-64-0 is a valid CAS Registry Number.
87769-64-0Relevant articles and documents
Brine Shrimp (Artemia salina) Lethality Bioassay of Some 2-(Alkyl/Aryl)-6-Phenyl-4,5-Dihydropyridazin-3(2H)-one Derivatives
Acharya, Mrityunjoy,Asif, Mohammad,Imran, Mohd,Kamal, Mehnaz
, p. 57 - 61 (2021/08/12)
A series of pyridazinone derivatives, 2-(alkyl/aryl)-6-phenyl-4,5-dihydropyridazin-3(2H)-ones (3a-h), was synthesized from 6-phenyl-4,5-dihydropyridazin-3(2H)-one (2). Compound 2 was synthesized from benzoylpropionic acid (1). The synthesized compounds were characterized on the basis of their spectral (infrared, proton nuclear magnetic resonance, carbon-13 nuclear magnetic resonance, and mass spectra) and elemental analytical data. The compounds 2 and 3a-h and potassium dichromate (as reference drug) were tested at the dose level of 10, 20, and 30 μg/mL. Compounds 3d and 3b exhibited potent brine shrimp lethality with LC50values of 4.023 μg and 4.20 μg. Other compounds 3g, 3f, 3c, 3h, 2, 3a, and 3e also showed significant cytotoxic activity with LC50values of 13.91, 12.58, 11.91, 11.76, 10.58, 9.76, and 7.46 μg, respectively. The present study supports that brine shrimp bioassay is a simple, reliable, and suitable method for estimation of bioactivity of synthesized compounds and provides support for their use in medicine.
HETEROCYCLIC COMPOUND AND USE THEREOF
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Paragraph 0685; 0686, (2013/06/05)
The present invention aims to provide a compound having a PDE inhibitory action and useful as a medicament for the prophylaxis or treatment of schizophrenia and the like. A compound represented by the formula (1x): wherein each symbol is as des