898754-24-0

Basic information

• Product Name: 3-(2,6-DIMETHYLPHENYL)PROPIOPHENONE
• Synonyms: 3-(2,6-DIMETHYLPHENYL)PROPIOPHENONE
• CAS NO: 898754-24-0
• Molecular Formula: C17H18O
• Molecular Weight: 238.32
• Mol File: 898754-24-0.mol

Chemical Properties

• Boiling Point: 387.7°C at 760 mmHg
• Flash Point: 168.7°C
• Appearance: /
• Density: 1.032g/cm³
• Vapor Pressure: 3.23E-06mmHg at 25°C
• Refractive Index: 1.564
• CAS DataBase Reference: 3-(2,6-DIMETHYLPHENYL)PROPIOPHENONE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2,6-DIMETHYLPHENYL)PROPIOPHENONE(898754-24-0)
• EPA Substance Registry System: 3-(2,6-DIMETHYLPHENYL)PROPIOPHENONE(898754-24-0)

Safety Data

• Hazardous Substances Data: 898754-24-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C17H18O/c1-13-7-6-8-14(2)16(13)11-12-17(18)15-9-4-3-5-10-15/h3-10H,11-12H2,1-2H3

Upstream product

• 98-85-1 1-Phenylethanol 
• 62285-58-9 2,6-dimethylbenzyl alcohol 
• 98-86-2 acetophenone 

Relevant articles and documents

Alkylation synthesis method of in-situ catalytic alcohol (by machine translation)

The method comprises VIB metal complexes, an auxiliary ligand and a base as a catalytic reaction system, wherein the alcohol serves as an alkylating agent, and the nucleophilic substrate is subjected to in-situ catalytic alkylation reaction in a solvent and an inert gas atmosphere. The catalytic system has a wide application range on a substrate, can catalyze the synthesis of C-N and C-C bond compounds of different structures under mild conditions, and can green synthesize a series of valuable N - alkylation and C - alkylation compounds. (by machine translation)

Sustainable and Selective Alkylation of Deactivated Secondary Alcohols to Ketones by Non-bifunctional Pincer N-heterocyclic Carbene Manganese

A sustainable and green route to access diverse functionalized ketones via dehydrogenative–dehydrative cross-coupling of primary and secondary alcohols is demonstrated. This borrowing hydrogen approach employing a pincer N-heterocyclic carbene Mn complex displays high activity and selectivity. A variety of primary and secondary alcohols are well tolerant and result in satisfactory isolated yields. Mechanistic studies suggest that this reaction proceeds via a direct outer-sphere mechanism and the dehydrogenation of the secondary alcohol substrates plays a vital role in the rate-limiting step.

Nonbifunctional Outer-Sphere Strategy Achieved Highly Active α-Alkylation of Ketones with Alcohols by N-Heterocyclic Carbene Manganese (NHC-Mn)

The unusual nonbifunctional outer-sphere strategy was successfully utilized in developing an easily accessible N-heterocyclic carbene manganese (NHC-Mn) system for highly active α-alkylation of ketones with alcohols. This system was efficient for a wide range of ketones and alcohols under mild reaction conditions, and also for the green synthesis of quinoline derivatives. The direct outer-sphere mechanism and the high activity of the present system demonstrate the potential of nonbifunctional outer-sphere strategy in catalyst design for acceptorless dehydrogenative transformations.