898760-99-1Relevant academic research and scientific papers
Triphenylphosphine [...]link iridium hydrogen adduct and its preparation and use
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Paragraph 0049; 0050, (2017/03/08)
The invention discloses a benzo-quinoline triphenylphosphine ring iridium hydride adduct. The compound has the general formula in the specification, wherein R is H,-CH3,-OCH3,-C6H5 or-CHO, and R is positioned in the position of 3, 5, 6 or 8 of benzo-quinoline. The preparation steps of the compound are as follows: taking a benzo-quinoline derivative, iridium trichloride and triphenylphosphine, adding into a solvent, performing heating reflux under gas protection, and filtering after the end of the reaction to obtain the benzo-quinoline triphenylphosphine ring iridium hydride adduct. The prepared benzo-quinoline triphenylphosphine ring iridium hydride adduct is a high-activity catalyst which can catalyze the reaction of aryl alkyne and aryl benzyl alcohol to obtain an aryl ketone compound. The benzo-quinoline triphenylphosphine ring iridium hydride adduct is taken as a metal catalyst, the using quantity of the catalyst is small, a cheap weak base is used, and then the reaction of the aryl alkyne and the aryl benzyl alcohol can be catalyzed efficiently. The method has the advantages of mild reaction conditions, wide range of reaction substrates, economy, high efficiency and the like, and further has important application values.
Replacing a stoichiometric silver oxidant with air: Ligated Pd(II)-catalysis to β-aryl carbonyl derivatives with improved chemoselectivity
Vellakkaran, Mari,Andappan, Murugaiah M.S.,Kommu, Nagaiah
supporting information, p. 2788 - 2797 (2014/05/06)
Air was employed as a green reoxidant of Pd(0), replacing stoichiometric and toxic silver salt, in the chelation-controlled Pd(II)-modulated arylative enolization of prop-2-en-1-ols to acquire synthetically-important β-aryl carbonyl derivatives. This green approach, which didn't require acid or base, allowed the compatibility of a range of functionalities (inclusive of -I, -Br & -Cl), resulting in the construction of structurally-diverse dihydrochalcones, α-benzyl-α′-alkyl acetones, α-benzyl β-keto esters and dihydrocinnamaldehydes. In addition to organoboronic acids, efficient coupling was also achieved with boronic esters and trifluoroborate salts. A deuterium labelling experiment revealed an interesting 1,2-hydrogen shift after β-arylation in the catalytic process. the Partner Organisations 2014.
