898796-17-3 Usage
Uses
Used in Pharmaceutical Industry:
6-(3,4-DiMethoxyphenyl)-3-pyridinecarbaldehyde is used as a reagent in the synthesis of various pharmaceuticals and organic compounds. Its unique chemical structure allows it to be a key component in the development of new drugs and therapeutic agents.
Used in Organic Synthesis:
6-(3,4-DiMethoxyphenyl)-3-pyridinecarbaldehyde is used as a reagent in organic synthesis for the preparation of various organic compounds. Its versatility and unique properties make it a valuable tool in the synthesis of complex organic molecules.
Used in Antioxidant Applications:
6-(3,4-DiMethoxyphenyl)-3-pyridinecarbaldehyde is used as an antioxidant due to its ability to neutralize free radicals and prevent oxidative damage. This makes it a potential candidate for use in various applications, such as food preservation, cosmetics, and pharmaceuticals, where antioxidant properties are desired.
Used in Antimicrobial Applications:
6-(3,4-DiMethoxyphenyl)-3-pyridinecarbaldehyde is used as an antimicrobial agent due to its ability to inhibit the growth of various microorganisms. This makes it a potential candidate for use in applications such as disinfectants, sanitizers, and preservatives in various industries.
Used in Research and Development:
6-(3,4-DiMethoxyphenyl)-3-pyridinecarbaldehyde is used in research and development for the study of its potential pharmacological properties. Its unique chemical structure and biological activities make it an interesting compound for further investigation and development of new therapeutic agents and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 898796-17-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,9,8,7,9 and 6 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 898796-17:
(8*8)+(7*9)+(6*8)+(5*7)+(4*9)+(3*6)+(2*1)+(1*7)=273
273 % 10 = 3
So 898796-17-3 is a valid CAS Registry Number.
898796-17-3Relevant academic research and scientific papers
BIARYLRHODANINE AND PYRIDYLRHODANINE COMPOUNDS AND THEIR USE
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Page/Page column 83, (2010/04/06)
The present invention pertains generally to the field of therapeutic compounds, and more specifically to compounds related to rhodanine, which compounds are inter alia inhibitors and/or binders of antiapoptotic/pro-survival Bcl-2 proteins such as Bcl-XL and/or Mcl-1. More specifically, the present invention is concerned with Rhodanine- based Pan-Bcl-2 inhibitors and Mcl-1 -specific inhibitors as anti-cancer compounds. The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and invivo, to inhibit and/or bind Bcl-2 proteins such as Bcl-XL and/or Mcl-1, and in the treatment of diseases and conditions that are mediated by Bcl-2 proteins, that are ameliorated by the inhibition of Bcl-2 protein function (such as Bcl-XL and/or Mcl-1 ) including proliferative conditions such as cancer, optionally in combination with another agent.
Structural insights into the design of small molecule inhibitors that selectively antagonize Mcl-1
Bernardo, Paul H.,Sivaraman, Thirunavukkarasu,Wan, Kah-Fei,Xu, Jin,Krishnamoorthy, Janarthanan,Sons, Chun Meng,Tian, Liming,Chin, Jasmine S. F.,Lim, Diane S. W.,Mok, Henry Y. K.,Yu, Victor C.,Tong, Joo Chuan,Chai, Christina L. L.
supporting information; experimental part, p. 2314 - 2318 (2010/08/06)
The screening of a small focused library of rhodanine derivatives as inhibitors of Bcl-2 proteins led to the discovery of two structurally related compounds with different binding profiles against the Bcl-XL and the Mcl-1 proteins. Subsequent NMR studies with mutant proteins and in silico docking studies provide a possible rationale for the observed specificity.
