89901-71-3

Upstream product

• 1809-20-7 diisopropyl hydrogenphosphonate 
• 2700-22-3 Benzylidenemalononitrile 
• 116-17-6 triisopropyl phosphite 
• 100-52-7 benzaldehyde 
• 109-77-3 malononitrile 
• 88542-86-3 diisopropyl hydrogen phosphite 

Downstream Products

• 89901-65-5 <α-(diisopropoxyphosphinyl)benzylidene>malononitrile 

Relevant academic research and scientific papers

Recoverable phospha-michael additions catalyzed by a 4-n,n-dimethylaminopyridinium saccharinate salt or a fluorous long-chained pyridine: Two types of reusable base catalysts

Phospha-Michael addition, which is the addition reaction of a phosphorus-based nucleophile to an acceptor-substituted unsaturated bond, certainly represents one of the most versatile and powerful tools for the formation of P-C bonds, since many different

Efficient, Solvent-Free, Multicomponent Method for Organic-Base-Catalyzed Synthesis of β-Phosphonomalonates

An efficient, one-pot, di-n-butylamine-catalyzed, three-component synthesis of β-phosphonomalonates has been developed. A wide range of substrates, including aromatic and fused aromatic aldehydes, were condensed with enolizable C-H activated compounds and dialkylphosphites to give the desired products in excellent yields. This method provides an eco-friendly alternative approach to rapid construction of a diversity-oriented library of β-phosphonomalonates.

Novel ionic tagged amine anchored on magnetic nanoparticles: An efficient and magnetically recyclable catalyst for Phospha-Michael addition

Ionic tagged propyl amine immobilized on magnetic nanoparticles (MNPs) was synthesized and fully characterized. The novel catalyst (MNPs@PA-IL) was applied in phospha-Michael addition and gave the desired β-phosphonomalonates in good yields. The MNPs supported catalyst with ionic tag could be readily recovered from the reaction mixture using an external magnet. Compared with ionic-free counterpart (MNPs@PA), MNPs@PA-IL present better catalytic activity. The proposed mechanism regarding the MNPs@PA-IL catalyzed phospha-Michael reaction was also discussed.

Silica-bonded 2-hydroxyethylammonium acetate as an efficient and recyclable catalyst for the synthesis of 2-amino-4H-chromen-4-yl phosphonates and β-phosphonomalonates

Silica-bonded 2-hydroxyethylammonium acetate was synthesized easily by the reaction of 3-chloropropylsilica with ethanolamine followed by ion exchange with acetate. It was used as a heterogeneous, re-usable, efficient and easy to handle catalyst for the one-pot synthesis of a variety of 2-Amino-4H-chromen-4- yl phosphonates and β-phosphonomalonates at room temperature under solvent-free conditions. Graphical Abstract: [Figure not available: see fulltext.]

Phospha-Michael addition of diethyl phosphite to α,β-unsaturated malonates catalyzed by nano γ-Fe2O3-pyridine based catalyst as a new magnetically recyclable heterogeneous organic base

Nano γ-Fe2O3-pyridine based catalyst as a new magnetically recyclable heterogeneous organic base was synthesized. The synthesized odorless pyridine based catalyst was used as a new catalyst for the efficient synthesis of β-phosphonom

Phosphomolybdic acid: An efficient and reusable catalyst for the synthesis of β- Phosphono malonates

Phosphomolybdic acid (H3PMo12O40) is an efficient and reusable catalyst for the synthesis of the phospha-Michael addition of phosphite esters with different types of α,β- Unsaturated malonates to produce a variety of β- Ph

Phospha-Michael addition of phosphorus nucleophiles to α,β- unsaturated malonates using 3-aminopropylated silica gel as an efficient and recyclable catalyst

3-Aminopropylated silica gel, which is prepared from commercially available and cheap starting materials, is introduced as an efficient and recyclable catalyst for the phospha-Michael addition of phosphorus nucleophiles to α,β-unsaturated malonates. Short

P-C Bond formation via direct and three-component conjugate addition catalyzed by 1,5,7-triazabicyclo[4.4.0]dec-5-ene (TBD)

The direct addition of P(O)-H bonds (dialkyl phosphites and diphenyl phosphonite) across various activated alkenes was catalyzed effectively by 1,5,7-triazabicyclo[4.4.0]dec-5-ene (TBD). This is a mild, rapid and efficient protocol to generate P-C bonds.