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4-methoxy-N-(4-(methylthio)phenyl)benzamide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

899017-70-0

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899017-70-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 899017-70-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,9,9,0,1 and 7 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 899017-70:
(8*8)+(7*9)+(6*9)+(5*0)+(4*1)+(3*7)+(2*7)+(1*0)=220
220 % 10 = 0
So 899017-70-0 is a valid CAS Registry Number.

899017-70-0Downstream Products

899017-70-0Relevant academic research and scientific papers

Novel 5-substituted 1H-tetrazoles as cyclooxygenase-2 (COX-2) inhibitors

Al-Hourani, Baker Jawabrah,Sharma, Sai Kiran,Suresh, Mavanur,Wuest, Frank

, p. 2235 - 2238 (2012)

A series of novel 5-substituted 1H-tetrazoles as cyclooxygenase-2 (COX-2) inhibitors was prepared via treatment of various diaryl amides with tetrachlorosilane/sodium azide. All compounds were tested in cyclooxygenase (COX) assays in vitro to determine COX-1 and COX-2 inhibitory potency and selectivity. Tetrazoles contained a methylsulfonyl or sulfonamide group as COX-2 pharmacophore displayed only low inhibitory potency towards COX-2. Most potent compounds showed IC50 values of 6 and 7 μM for COX-2. All compounds showed IC50 values greater 100 μM for COX-1 inhibition.

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