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89929-27-1

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  • 9,10-dihydroxy-3-isobutyl-3,4,6,7-tetrahydro-1H-pyrido[2,1-a]isoquinolin-2(11bH)-one

    Cas No: 89929-27-1

  • USD $ 1.2-5.0 / Kiloliter

  • 5 Kiloliter

  • 3000 Metric Ton/Month

  • Chemwill Asia Co., Ltd.
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89929-27-1 Usage

Description

9,10-dihydroxy-3-isobutyl-3,4,6,7-tetrahydro-1H-pyrido[2,1-a]isoquinolin-2(11bH)-one is a complex organic compound belonging to the class of isoquinoline alkaloids. It features a pyridoisoquinoline skeleton with a dihydroxy group at the 9th and 10th positions and an isobutyl group at the 3rd position. 9,10-dihydroxy-3-isobutyl-3,4,6,7-tetrahydro-1H-pyrido[2,1-a]isoquinolin-2(11bH)-one is synthesized from natural sources and exhibits a range of pharmacological activities, such as anticancer, antimicrobial, and anti-inflammatory properties. Its potential therapeutic applications in treating various diseases and disorders make it a significant compound in medicinal chemistry research.

Uses

Used in Pharmaceutical Industry:
9,10-dihydroxy-3-isobutyl-3,4,6,7-tetrahydro-1H-pyrido[2,1-a]isoquinolin-2(11bH)-one is used as a pharmaceutical agent for its anticancer properties. It targets various types of cancer cells and can be utilized in combination with conventional chemotherapeutic drugs to enhance their efficacy and overcome drug resistance.
Used in Antimicrobial Applications:
In the field of antimicrobial research, 9,10-dihydroxy-3-isobutyl-3,4,6,7-tetrahydro-1H-pyrido[2,1-a]isoquinolin-2(11bH)-one serves as an antimicrobial agent, effective against a range of bacteria and other pathogens. Its ability to inhibit microbial growth makes it a promising candidate for the development of new antibiotics and antifungal agents.
Used in Anti-inflammatory Applications:
9,10-dihydroxy-3-isobutyl-3,4,6,7-tetrahydro-1H-pyrido[2,1-a]isoquinolin-2(11bH)-one is employed as an anti-inflammatory agent, demonstrating potential in reducing inflammation and alleviating symptoms associated with various inflammatory conditions. Its anti-inflammatory properties make it a valuable compound for the development of new therapeutics to treat chronic inflammatory diseases.

Check Digit Verification of cas no

The CAS Registry Mumber 89929-27-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,9,9,2 and 9 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 89929-27:
(7*8)+(6*9)+(5*9)+(4*2)+(3*9)+(2*2)+(1*7)=201
201 % 10 = 1
So 89929-27-1 is a valid CAS Registry Number.

89929-27-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Oxo-3-isobutyl-9,10-dihydroxy-1,2,3,4,6,7-hexahydro-11bH-benzo<a>chinolizin

1.2 Other means of identification

Product number -
Other names 2-Oxo-3-isobutyl-9,10-dihydroxy-1,2,3,4,6,7-hexahydro-11bH-benzo[a]chinolizin

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:89929-27-1 SDS

89929-27-1Relevant articles and documents

Novel Process for Preparation of Tetrabenazine and Deutetrabenazine

Ray, Purna Chandra,Pawar, Yogesh Dadaji,Singare, Dnyaneshwar Tukaram,Deshpande, Tushar Nandkumar,Singh, Girij Pal

supporting information, p. 520 - 526 (2018/04/27)

A novel process for the synthesis of tetrabenazine (1) and deutetrabenazine (2), two well-known drugs used for the treatment of chorea associated with Huntington's disease, has been developed. All of the reaction parameters were optimized through a series of reactions and by using Design of Experiment techniques. The newly developed methods are industrially scalable and employ cheap, commercially available raw materials and hence are highly efficient. The added advantage is that the developed processes evade the use of genotoxic alkylating agents and therefore could be considered as safe and viable alternatives to the existing methods.

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