89929-99-7Relevant articles and documents
Total Synthesis of Nosiheptide
Wojtas, K. Philip,Riedrich, Matthias,Lu, Jin-Yong,Winter, Philipp,Winkler, Thomas,Walter, Sophia,Arndt, Hans-Dieter
, p. 9772 - 9776 (2016/08/10)
Total synthesis of the bismacrocyclic thiopeptide antibiotic nosiheptide was achieved through the assembly of a fully functionalized linear precursor followed by consecutive macrocyclizations. Key features are a critical macrothiolactonization and a mild deprotection strategy for the 3-hydroxypyridine core. The natural product was identical to isolated authentic material in terms of spectral data and antibiotic activity.
Heterocyclic substituted benzyl alcohol, insecticidal ester derivatives, and intermediates
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, (2008/06/13)
Disclosed and exemplified are insecticidal and acaricidal optionally substituted furylbenzyl, thienylbenzyl, pyrazinylbenzyl, or pyridinzylbenzyl esters of the pyrethroid acids, novel pyrethroid alcohols and other intermediates, and compositions, a method of use and a process for preparation of the esters.