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Usage

Uses

Used in Pharmaceutical Industry:
6-CHLORO-3,4-DIHYDRO-2(1H)-QUINOXALINONE is used as an intermediate in the synthesis of pharmaceuticals for its potential anti-inflammatory and antitumor properties. Its unique structure allows for the development of new drugs targeting various diseases and conditions.
Used in Agrochemical Industry:
6-CHLORO-3,4-DIHYDRO-2(1H)-QUINOXALINONE is used as an intermediate in the synthesis of agrochemicals due to its reported antibacterial and antifungal activities. This makes it a valuable compound in developing new pesticides and fungicides to protect crops and enhance agricultural productivity.
Used in Antibacterial Applications:
6-CHLORO-3,4-DIHYDRO-2(1H)-QUINOXALINONE is used as an antibacterial agent for its ability to combat bacterial infections. Its potential use in this area can contribute to the development of new antibiotics to address the growing issue of antibiotic resistance.
Used in Antifungal Applications:
6-CHLORO-3,4-DIHYDRO-2(1H)-QUINOXALINONE is used as an antifungal agent to treat fungal infections. Its potential in this area can lead to the creation of new antifungal medications, providing alternative treatment options for various fungal diseases.
Used in Anti-inflammatory Applications:
6-CHLORO-3,4-DIHYDRO-2(1H)-QUINOXALINONE is used as an anti-inflammatory agent for its potential to reduce inflammation and alleviate symptoms associated with inflammatory conditions. This can lead to the development of new therapeutic options for patients suffering from chronic inflammation and related disorders.

Upstream product

• 859307-61-2 ethyl 2-(4-chloro-2-nitrophenylamino)acetate 
• 34836-97-0 6-chloro-1,2-dihydro-2-oxoquinoxaline 4-oxide 
• 2427-71-6 6-chloro-1,2-dihydroquinoxalin-2-one 
• 95-83-0 4-Chloro-1,2-phenylenediamine 
• 610-40-2 3,4-dinitro-chlorobenzene 
• 700-37-8 4-chloro-2-fluoro-nitrobenzene 
• 34797-69-8 p-chloro-o-nitroacetoacetanilide 

Downstream Products

• 18671-97-1 2,6-dichloroquinoxaline 
• 463-72-9 carbamic chloride 

Relevant academic research and scientific papers

Palladium-catalyzed direct Hiyama arylation of quinoxalin-2(1H)-ones with aryl siloxanes in water

An efficient method for palladium-catalyzed direct Hiyama coupling of various quinoxalin-2(1H)-ones with aryl siloxanes has been developed. The protocol provides a convenient access to a variety of useful C3-arylated 1-methylquinoxalin-2(1H)-one derivatives in reasonable yields by using low cost water as a solvent and oxygen as an oxidant.

Synthesis and biological evaluation of N4-(hetero)arylsulfonylquinoxalinones as HIV-1 reverse transcriptase inhibitors

A series of novel N4-(hetero)arylsulfonylquinoxalinone derivatives were prepared in a straight and efficient way. Of all the synthesized compounds, five compounds exhibited potent anti-HIV-1 replication activities with IC50 value at

High-affinity partial agonist imidazo[1,5-a]quinoxaline amides, carbamates, and ureas at the γ-aminobutyric acid A/benzodiazepine receptor complex

A series of imidazo[1,5-a]quinoxaline amides, carbamates, and ureas which have high affinity for the γ-aminobutyric acid A/benzodiazepine receptor complex was developed. Compounds within this class have varying efficacies ranging from antagonists to full

Imidazo[1,5-A]quinoxalines

An invention relating to Imidazo[1,5-a]quinoxalines (I) STR1 which do not contain an endocyclic carbonyl group and which are useful as anxiolytic and sedative/hypnotic agents.

The facile one pot synthesis of 6-substituted 2(1H)-quinoxalinones

Facile one pot synthesis of 6-substituted 2(1H)-quinoxalinones and these reaction mechanisms are described.The intramolecular cyclization reaction of 4'-substituted 2'-nitroacetoacetanilides in aqueous basic medium and the reduction of 6-substituted 2(1H)-quinoxalinone-4-oxide wit sodium borohydride or sodium hydrogensulfite were studied in detail