2427-71-6

Usage

Uses

Used in Agricultural Industry:
2-Hydroxy-6-chloroquinoxaline is used as an intermediate for the production of herbicides. Its chemical properties, including the presence of a hydroxyl group and a chloro substituent, make it a valuable component in the synthesis of various herbicidal compounds. These herbicides are essential for controlling unwanted plant growth in agricultural settings, ensuring the healthy growth of crops and increasing overall yield.

InChI:InChI=1/C8H5ClN2O/c9-5-1-2-6-7(3-5)10-4-8(12)11-6/h1-4H,(H,11,12)

Upstream product

• 34836-97-0 6-chloro-1,2-dihydro-2-oxoquinoxaline 4-oxide 
• 924-44-7 glyoxylic acid ethyl ester 
• 95-83-0 4-Chloro-1,2-phenylenediamine 

Downstream Products

• 18671-97-1 2,6-dichloroquinoxaline 
• 1448-87-9 2-chloroquinoxaline 
• 89938-22-7 6-chloro-1,2,3,4-tetrahydroquinoxalin-2-one 
• 1315337-00-8 6-chloro-2-(perfluorophenyl)quinoxaline 

Relevant academic research and scientific papers

Electro-oxidative C-H alkylation of quinoxalin-2(1: H)-ones with organoboron compounds

Radical cleavage of C-B bonds to accomplish C-H functionalization is synthetically appealing but practically challenging. We report herein a mild electro-oxidative method for efficient C-H alkylation of quinoxalin-2(1H)-ones by means of radical addition reactions of alkyl boronic acids and esters and alkyl trifluoroborates to afford C-C coupled products. This journal is

(2-quinoxalinyloxy) phenoxypropanoic acids and related derivatives as anticancer agents

This invention relates to (2-quinoxalinyloxy)phenoxypropanoic acids, related derivatives thereof, enantiomeric and diastereomeric forms thereof, mixtures of enantiomeric diastereomeric forms thereof, and pharmaceutically acceptable salt forms thereof, pharmaceutical compositions containing them, processes for their preparation, and methods of using them to treat cancer, particularly solid tumors, in mammals.

The facile one pot synthesis of 6-substituted 2(1H)-quinoxalinones

Facile one pot synthesis of 6-substituted 2(1H)-quinoxalinones and these reaction mechanisms are described.The intramolecular cyclization reaction of 4'-substituted 2'-nitroacetoacetanilides in aqueous basic medium and the reduction of 6-substituted 2(1H)-quinoxalinone-4-oxide wit sodium borohydride or sodium hydrogensulfite were studied in detail