89938-62-5

Basic information

• Product Name: 2-CHLORO-5-(METHYLSULFONYL)BENZOIC ACID
• Synonyms: 2-Chloro-5-methanesulfonylbenzoic acid;1-Carboxy-2-chloro-5-(methylsulphonyl)benzene;2-Chloro-5-(methylsulphonyl)benzoic acid;Benzoic acid,2-chloro-5-(Methylsulfonyl)-
• CAS NO: 89938-62-5
• Molecular Formula: C₈H₇ClO₄S
• Molecular Weight: 234.66
• Mol File: 89938-62-5.mol
• Article Data: 5

Chemical Properties

• Melting Point: 82-85 °C
• Boiling Point: 462.9°C at 760 mmHg
• Flash Point: 233.7°C
• Appearance: /
• Density: 1.507±0.06 g/cm3(Predicted)
• Vapor Pressure: 2.29E-09mmHg at 25°C
• Storage Temp.: 2-8°C
• PKA: 2.26±0.25(Predicted)
• CAS DataBase Reference: 2-CHLORO-5-(METHYLSULFONYL)BENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-5-(METHYLSULFONYL)BENZOIC ACID(89938-62-5)
• EPA Substance Registry System: 2-CHLORO-5-(METHYLSULFONYL)BENZOIC ACID(89938-62-5)

Safety Data

• Hazardous Substances Data: 89938-62-5(Hazardous Substances Data)

Usage

General Description

2-Chloro-5-(methylsulfonyl)benzoic acid is a chemical compound that belongs to the benzoic acid class. It is a white crystalline solid and is listed as an organic intermediate in chemical synthesis. 2-CHLORO-5-(METHYLSULFONYL)BENZOIC ACID is primarily used as an intermediate for the production of pharmaceuticals, agrochemicals, and dyes. It possesses a chlorine group and a methylsulfonyl group, making it a useful building block for the development of various chemical compounds. Additionally, it is a valuable reagent in organic chemistry for the synthesis of complex molecules and pharmaceuticals.

InChI:InChI=1/C8H7ClO4S/c1-14(12,13)5-2-3-7(9)6(4-5)8(10)11/h2-4H,1H3,(H,10,11)/p-1

Upstream product

• 89692-75-1 2-Chloro-5-sulfino-benzoic acid 
• 74-88-4 methyl iodide 
• 51546-12-4 2-chloro-5-(methylthio)benzoic acid 
• 886973-19-9 methyl 2-chloro-5-methylsulfanyl-benzoate 

Downstream Products

• 90222-79-0 2-amino-5-(methylsulfonyl)benzoic acid 
• 845616-02-6 2-isopropoxy-5-methanesulfonyl-benzoic acid 

Relevant articles and documents

PROTEIN-MACROMOLECULE CONJUGATES AND METHODS OF USE THEREOF

The present disclosure provides protein-macromolecule conjugates, releasable linkers, and macromolecules, as defined herein. The disclosed conjugates provide unique properties that are based at least upon the properties of linker and number of linker-Macromolecule moieties. Also provided herein are a method of synthesis and use of conjugates in treating diseases and disorders.

1- (2-AMINO-BENZOL) -PIPERAZINE DERIVATIVES AS GLYCINE UPTAKE INHIBITORS FOR THE TREATMENT OF PSYCHOSES

A compound of formula (I) wherein the substituents are described in claim 1 for the treatment of psychoses, pain, neurodegenerative disfunction in memory and learning, schizophrenia, dementia and other diseases in which cognitive processes are impaired, such as attention deficit disorders or Alzheimer's disease.

Substituted N-cycloalkylmethyl-1H-pyrazolo(3,4-b)quinolin-4 amines and compositions and methods of use thereof

Substituted N-cycloalkylmethyl-1H-pyrazolo[3,4-b]quinolin-4-amines, pharmaceutical compositions containing them and methods for a) effecting c-GMP-phosphodiesterase inhibition, b) treating heart failure and/or hypertension, c) reversing or reducing nitrate-induced tolerance and d) treating angina pectoris, congestive heart disease and myocardial infarction utilizing them.