899422-33-4Relevant academic research and scientific papers
Selective functionalization of imidazoles via an iodine-copper exchange reaction
Yang, Xiaoyin,Knochel, Paul
, p. 2170 - 2172 (2008/03/14)
The reaction of protected 4,5-diiodoimidazoles with (PhMe 2CCH2)2CuLi regioselectively provides 5-cuprated imidazoles, which readily react with various electrophiles furnishing functionalized imidazoles in good yields; remarkably, these resulting mono-iodoimidazoles undergo again an iodine-copper exchange reaction in the presence of sensitive functional groups, like an aldehyde or a ketone. The Royal Society of Chemistry 2006.
Synthesis of 4-(dimethylamino)pyridinium-substituted pyrazine, pyridazine, 1,3,5-triazine, purine, and imidazole
Schmidt, Andreas,Mordhorst, Thorsten
, p. 1393 - 1400 (2007/10/03)
Substitution reactions of 2,3-dichloropyrazine, 3,6-dichloropyridazine, 2,4,6-trichloro-1,3,5-triazine, 2,6-dichloropurine, and N-tosyl-2,4,5-tribromoimidazole with 4-(dimethylamino)pyridine to monocationic, dicationic, and tricationic hetarenium salts ar
