1746-25-4

Basic information

• Product Name: 2,4,5-Triiodoimidazole
• Synonyms: 2,4,5-triiodo-imidazol;2,4,5-TRIIODO-1H-IMIDAZOLE;2,4,5-TRIIODOIMIDAZOLE
• CAS NO: 1746-25-4
• Molecular Formula: C₃HI₃N₂
• Molecular Weight: 445.77
• Product Categories: blocks;Imidazoles;Iodides;Imidazol&Benzimidazole;Imidaxoles
• Mol File: 1746-25-4.mol
• Article Data: 18

Chemical Properties

• Melting Point: 188-190°C
• Boiling Point: 459.2 °C at 760 mmHg
• Flash Point: 231.5 °C
• Appearance: /
• Density: 3.504 g/cm³
• Vapor Pressure: 1.29E-08mmHg at 25°C
• Refractive Index: 1.864
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 6.89±0.10(Predicted)
• CAS DataBase Reference: 2,4,5-Triiodoimidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4,5-Triiodoimidazole(1746-25-4)
• EPA Substance Registry System: 2,4,5-Triiodoimidazole(1746-25-4)

Safety Data

• Hazard Codes: Xn:Harmful
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• RIDADR: UN 2811 6.1/PG III
• RTECS: NI8680000
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 1746-25-4(Hazardous Substances Data)

Usage

Uses

suzuki reaction

InChI:InChI=1/C3HI3N2/c4-1-2(5)8-3(6)7-1/h(H,7,8)

Upstream product

• 288-32-4 1H-imidazole 
• 623-11-0 1-methyl-4-nitrosobenzene 
• 1072-84-0 3H-imidazole-4-carboxylic acid 
• 7553-56-2 iodine 
• 7732-18-5 water 

Downstream Products

• 71759-89-2 4-iodoimidazole 
• 216314-79-3 4,5-diiodo-1-[(2-(trimethylsilyl)ethoxy)methyl]-1H-imidazole 
• 3034-62-6 2-iodo-1H-imidazole 
• 899422-33-4 4,5-diiodo-1-(toluene-4-sulfonyl)-1H-imidazole 
• 71759-89-2 5-iodo-1H-imidazole 
• 15813-09-9 4,5-diiodo-1H-imidazole 
• 134420-44-3 1-<(Benzyloxy)methyl>-2,4,5-triiodoimidazole 

Relevant articles and documents

Mild and efficient iodination of aromatic and heterocyclic compounds with the NaClO2/NaI/HCl system

NaClO2/NaI in the presence of HCl is a mild, cheap, and non-toxic reagent for the iodination of phenols, including estradiol and naphthol, aromatic amines, and heterocyclic substrates, e.g., indoles, 8-hydroxyquinoline, imidazole, in fair to excellent yields by a very simple isolation protocol. The scope of the procedure is exemplified by the first iodination of 5-nitroindole to 3-iodo-5-nitroindole in 75% yield.

Ultrasound-promoted rapid and efficient iodination of aromatic and heteroaromatic compounds in the presence of iodine and hydrogen peroxide in water

A rapid and efficient ultrasound-promoted protocol for iodination of aromatic and heteroaromatic compounds, using molecular iodine in the presence of aqueous hydrogen peroxide in water without any cosolvent, has produced versatile iodinated organic molecules with potential application in organic synthesis and medicine in short reaction times and good to excellent yields. Copyright

Efficient and eco-friendly synthesis of iodinated aromatic building blocks promoted by iodine and hydrogen peroxide in water: A mechanistic investigation by mass spectrometry

The reaction of aromatic and heteroaromatic compounds with molecular iodine in the presence of aqueous hydrogen peroxide using water without any co-solvent at 50 °C for 24 h produced versatile iodinated organic molecules with potential application in organic synthesis and medicine in very good yields. In addition, a mechanistic investigation for the iodination process was carried out by mass spectrometry.