899429-04-0

Basic information

• Product Name: 6-BROMO-8-METHYL[1,2,4]TRIAZOLO[1,5-A]PYRIDINE
• Synonyms: 6-BROMO-8-METHYL[1,2,4]TRIAZOLO[1,5-A]PYRIDINE;6-broMo-8-Methyl-[1
• CAS NO: 899429-04-0
• Molecular Formula: C₇H₆BrN₃
• Molecular Weight: 212.04664
• Mol File: 899429-04-0.mol

Chemical Properties

• Appearance: /
• Density: 1.767g/cm³
• Refractive Index: 1.715
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 6-BROMO-8-METHYL[1,2,4]TRIAZOLO[1,5-A]PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-BROMO-8-METHYL[1,2,4]TRIAZOLO[1,5-A]PYRIDINE(899429-04-0)
• EPA Substance Registry System: 6-BROMO-8-METHYL[1,2,4]TRIAZOLO[1,5-A]PYRIDINE(899429-04-0)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 899429-04-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
6-Bromo-8-methyl[1,2,4]triazolo[1,5-a]pyridine is used as a pharmaceutical agent for its potential anti-inflammatory properties, offering a new avenue for the treatment of inflammation-related conditions. Its ability to modulate inflammatory pathways makes it a candidate for further exploration and development in this therapeutic area.
Used in Anticancer Applications:
In the field of oncology, 6-Bromo-8-methyl[1,2,4]triazolo[1,5-a]pyridine is utilized as an anticancer agent, targeting various types of cancer cells. Its potential to disrupt cancer cell proliferation and induce apoptosis positions it as a valuable compound for the development of novel cancer therapies.
Used in Antiviral Applications:
6-Bromo-8-methyl[1,2,4]triazolo[1,5-a]pyridine is employed as an antiviral agent, leveraging its ability to inhibit viral replication and reduce viral load in infected cells. This makes it a candidate for the development of new antiviral drugs to combat viral infections.
Used in Agrochemical Industry:
In the agrochemical sector, 6-Bromo-8-methyl[1,2,4]triazolo[1,5-a]pyridine is used as a bioactive compound for its potential to control pests and diseases in agriculture. Its ability to target and disrupt biological processes in pests and pathogens makes it a candidate for the development of new agrochemicals to improve crop protection and yield.

InChI:InChI=1/C7H6BrN3/c1-5-2-6(8)3-11-7(5)9-4-10-11/h2-4H,1H3

Upstream product

• 3430-21-5 5-bromo-3-methyl-pyridin-2-ylamine 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 883052-76-4 N'-(5-bromo-3-methyl-pyridin-2-yl)-N,N-dimethyl-formamidine 

Relevant articles and documents

[1,2,4]TRIAZOLO[1,5-A]PYRIDINYL SUBSTITUTED INDOLE COMPOUNDS

Disclosed are compounds of Formula (I) or a salt thereof, wherein R1, R2, R3, R4, R5, m, n, and p are defined herein. Also disclosed are methods of using such compounds as inhibitors of signaling through Toll-like receptor 7, or 8, or 9, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating inflammatory and autoimmune diseases.

(2S,3S)-3-amino-4-(3,3-difluoropyrrolidin-1-yl)-N,N-dimethyl-4-oxo-2-(4-[1, 2,4]triazolo[1,5-a]-pyridin-6-ylphenyl)butanamide: A selective α-amino amide dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes

A series of β-substituted biarylphenylalanine amides were synthesized and evaluated as inhibitors of dipeptidyl peptidase IV (DPP-4) for the treatment of type 2 diabetes. Optimization of the metabolic profile of early analogues led to the discovery of (2S