89943-11-3

Usage

Uses

Used in Pharmaceutical Industry:
5-Ethoxypyridin-2-amine serves as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows for the development of new drugs with potential therapeutic applications, making it a valuable component in medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical sector, 5-ethoxypyridin-2-amine is utilized as an intermediate for the production of pesticides and other crop protection agents. Its chemical properties enable the creation of effective and targeted agrochemicals to enhance crop yield and protect against pests.
Used in Dye and Pigment Production:
5-Ethoxypyridin-2-amine is also employed in the dye and pigment industry due to its ability to form colored compounds. It contributes to the development of new dyes and pigments for various applications, including textiles, plastics, and printing inks.
Overall, 5-ethoxypyridin-2-amine's diverse applications across different industries highlight its importance as a versatile chemical intermediate, with potential for further exploration and development in various fields.

Upstream product

• 74-96-4 ethyl bromide 
• 69634-17-9 N-(5-hydroxy-pyridin-2-yl)benzamide 
• 14773-50-3 3-ethoxypyridine 
• 89694-54-2 2-bromo-3-ethoxypyridine 
• 35771-41-6 6-[2-(4-nitrophenyl)diazenyl]-3-pyridinol 
• 898561-65-4 N-(5-ethoxypyridin-2yl)pivalamide 
• 42834-01-5 2-bromo-5-ethoxy-pyridine 
• 109-00-2 3-HYDROXYPYRIDINE 
• 137347-01-4 3-ethoxy-2-bromo-6-nitro-pyridine 
• 74037-50-6 3-ethoxy-2-nitropyridine 
• 626-55-1 3-Bromopyridine 

Downstream Products

• 42834-01-5 2-bromo-5-ethoxy-pyridine 
• 1356000-21-9 {1-[4-(6-ethoxy-3-phenyl-imidazo[1,2-a]pyridin-2-yl)-phenyl]-cyclobutyl}-carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

ANTIVIRAL DRUGS FOR TREATMENT OF ARENA VIRUS INFECTION

Compounds, methods and pharmaceutical compositions for treating viral infections, by administering certain compounds in therapeutically effective amounts are disclosed. Methods for preparing the compounds and methods of using the compounds and pharmaceutical compositions thereof are also disclosed. In particular, the treatment and prophylaxis of viral infections such as caused by the Arenavirus family such as Lassa fever, Argentine hemorrhagic fever, Bolivian hemorrhagic fever, and Venezuelan hemorrhagic fever

Copper(I)-catalyzed amination of aryl halides in liquid ammonia

The amination of aryl halides in liquid ammonia (LNH3) is catalyzed by a copper(I) salt/ascorbate system to yield primary aromatic amines in good to excellent yields. The low concentrations of catalyst required and the ease of product isolation suggest that this process has potential industrial applications. Commonly used ligands for analogous metal-catalyzed reactions are not effective. The rate of amination of iodobenzene in liquid ammonia is first order in copper(I) catalyst concentration. The small Hammett I? = 0.49 for the amination of 4-substituted iodobenzenes in liquid ammonia at 25 °C indicates that the C-I bond is not significantly broken in the transition state structure and that there is a small generation of negative charge in the aryl ring, which is compatible with the oxidative addition of the copper ion being rate limiting.

PYRAZOLES USEFUL IN THE TREATMENT OF INFLAMMATION

There is provided compounds of formula (I), wherein R1, R2, X1, X2 and n have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of a lipoxygenase (e.g. 15-lipoxygenase) is desired and/or required, and particularly in the treatment of inflammation.

TRIAZOLE COMPOUNDS AS LIPOXYGENASE INHIBITORS

There is provided compounds of formula (I) wherein W is an optionally substituted aryl or heteroaryl group, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of a lipoxygenase (e.g. 15- lipoxygenase) is desired and/or required, and particularly in the treatment of inflammation.

Positive allosteric modulators of the nicotinic acetylcholine receptor

The invention provides compounds of Formula I: These compounds may be in the form of pharmaceutical salts or compositions, may be in pure enantiomeric form or racemic mixtures, and are useful in pharmaceuticals used to treat diseases or conditions in which α7 nAChR is known to be involved.