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2-Hydroxy-2-pyridyl ethylamine, also known as HPEA, is a chemical compound with a diverse range of applications, primarily in the pharmaceutical industry. It functions as a chelating agent, capable of binding to metal ions, particularly copper, which plays a significant role in various physiological processes. HPEA's potential as a therapeutic agent for diseases related to copper toxicity, such as Wilson's disease and neurodegenerative disorders, highlights its importance in medical research. Furthermore, its antioxidant and anti-inflammatory properties make it a promising candidate for future drug development, although more research is required to fully elucidate its biological effects and clinical applications.

89943-14-6

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89943-14-6 Usage

Uses

Used in Pharmaceutical Industry:
2-Hydroxy-2-pyridyl ethylamine is used as a chelating agent for sequestering metal ions, especially copper, in biological systems. This function is crucial for the regulation of physiological processes and the management of diseases associated with copper toxicity.
Used in Treatment of Copper Toxicity Diseases:
In the medical field, 2-Hydroxy-2-pyridyl ethylamine is used as a therapeutic agent for treating diseases related to copper toxicity, such as Wilson's disease. Its ability to bind copper ions helps in mitigating the symptoms and progression of these conditions.
Used in Neurodegenerative Disorder Management:
2-Hydroxy-2-pyridyl ethylamine is also being studied for its potential role in managing neurodegenerative disorders, where copper toxicity may play a contributing factor. Its chelating properties could offer a therapeutic approach to alleviate the effects of these diseases.
Used in Antioxidant and Anti-Inflammatory Drug Development:
HPEA's potential antioxidant and anti-inflammatory properties make it a promising molecule for the development of new drugs. Its capacity to combat oxidative stress and inflammation could lead to innovative treatments for a variety of conditions.
Further research is necessary to fully understand the biological effects of 2-Hydroxy-2-pyridyl ethylamine and to explore its potential clinical applications, ensuring the safe and effective use of 2-HYDROXY-2-PYRIDYL ETHYLAMINE in various therapeutic areas.

Check Digit Verification of cas no

The CAS Registry Mumber 89943-14-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,9,9,4 and 3 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 89943-14:
(7*8)+(6*9)+(5*9)+(4*4)+(3*3)+(2*1)+(1*4)=186
186 % 10 = 6
So 89943-14-6 is a valid CAS Registry Number.

89943-14-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-amino-1-pyridin-2-ylethanol

1.2 Other means of identification

Product number -
Other names 2-Hydroxy-2-pyridylethylamine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:89943-14-6 SDS

89943-14-6Downstream Products

89943-14-6Relevant academic research and scientific papers

Easy kinetic resolution of some β-amino alcohols by Candida antarctica lipase B catalyzed hydrolysis in organic media

Alalla, Affef,Merabet-Khelassi, Mounia,Riant, Olivier,Aribi-Zouioueche, Louisa

, p. 1253 - 1259 (2016/11/23)

Herein, we present an easy and eco-friendly pathway to obtain some enantiomerically enriched β-amino alcohols using essentially as β-blockers. The enzymatic hydrolysis is conducted in hydrophobic organic media, assisted by sodium carbonate and CAL-B. We describe a new and effective procedure in terms of the chemo- and enantioselectivity, which allows for the formation of both enantiomers: the 2-acetamido-1-arylacetates and 2-acetamido-1-arylethanols were obtained with high ee values (up to >99%), while the selectivities reached E >200. The obtained results show a high CAL-B affinity toward the deacylation of the 2-acetamido-1-arylacetates compared to the acylation one. The structure of the 2-acetamido-1-arylacetates had a significant influence on both reactivity and selectivity of the CAL-B catalyzed deacylation. A multigram scale O-deacylation of racemic 2-acetamido-1-phenylacetate has been carried out, giving access both enantiomers with high enantiomeric purity and good isolated chemical yields.

PYRIMDINE COMPOUNDS USEFUL AS KINASE INHIBITORS

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Page/Page column 46, (2010/11/30)

A compound of formula (I) or a salt or solvate thereof: Formula (1) compositions and medicaments containing the same, as well as processes for the preparation and use of such compounds, compositions and medicaments. Such mono-anilino pyrimidine derivative

Oxazinoquinolones useful for the treatment of viral infections

-

, (2008/06/13)

The present invention provides a compound of formula I which is useful as antiviral agents, in particular, as agents against viruses of the herpes family.

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