899431-79-9

Basic information

• Product Name: (2R,3S)-1-Benzyl-3-benzyloxy-2-((3aR,5R,6S,6aR)-6-benzyloxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-pyrrolidine
• Synonyms: (2R,3S)-1-Benzyl-3-benzyloxy-2-((3aR,5R,6S,6aR)-6-benzyloxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-pyrrolidine
• CAS NO: 899431-79-9
• Molecular Weight: 515.649
• Mol File: 899431-79-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R,3S)-1-Benzyl-3-benzyloxy-2-((3aR,5R,6S,6aR)-6-benzyloxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-pyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3S)-1-Benzyl-3-benzyloxy-2-((3aR,5R,6S,6aR)-6-benzyloxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-pyrrolidine(899431-79-9)
• EPA Substance Registry System: (2R,3S)-1-Benzyl-3-benzyloxy-2-((3aR,5R,6S,6aR)-6-benzyloxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-pyrrolidine(899431-79-9)

Safety Data

• Hazardous Substances Data: 899431-79-9(Hazardous Substances Data)

Upstream product

• 299409-44-2 N-benzyl-3-O-benzyl-5-deoxy-5-(hydroxylamino)-5-vinyl-1,2-O-isopropylidene-α-D-gluco-1,4-pentofuranoside 
• 299409-50-0 (R)-N-benzyl-1-((3aR,5R,6S,6aR)-6-(benzyloxy)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)prop-2-en-1-amine 
• 162740-21-8 (Z)-N-benzyl-(3-O-benzyl-1,2-O-isopropylidene-α-D-xylofuranos-5-ylidene)amine N-oxide 
• 899431-87-9 Benzyl-[(R)-1-((3aR,5R,6S,6aR)-6-benzyloxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-2-hydroxy-but-3-enyl]-carbamic acid benzyl ester 
• 899431-69-7 3-O-benzyl-1,2-O-isopropylidene-5,6,7-trideoxy-5-(N-benzyl-N-benzoxycarbonylamino)-α-D-gluco-6-eno-hepta-1,4-furanose 
• 899431-70-0 Benzyl-[(S)-1-((3aR,5R,6S,6aR)-6-benzyloxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-2-oxo-ethyl]-carbamic acid benzyl ester 
• 899431-77-7 3-O-benzyl-1,2-O-isopropylidene-5,7,8-trideoxy-5-(N-benzylamino)-(5-N,6(S)-O-carbonyl)-α-L-glycero-D-gluco-7-eno-oct-1,4-furanose 
• 899431-78-8 (1R,2S)-1-Benzylamino-1-((3aR,5R,6S,6aR)-6-benzyloxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-but-3-en-2-ol 

Downstream Products

• 79831-76-8 (1S,6S,7R,8R,8aR)-2,6,7,8-tetrahydroxy-indolizidine 
• 899431-83-5 (2R,3S)-3-Hydroxy-2-((3aR,5R,6S,6aR)-6-hydroxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-pyrrolidine-1-carboxylic acid benzyl ester 

Relevant articles and documents

Intramolecular 5-endo-trig aminomercuration of β-hydroxy-γ- alkenylamines: Efficient route to a pyrrolidine ring and its application for the synthesis of (+)-castanospermine and analogues

The intramolecular aminomercuration reaction of sugar-derived β-hydroxy-γ-alkenylamines 8a-c undergoes 5-endo-trig cyclization in high yield. The sugar-substituted pyrrolidines thus obtained were elaborated to the synthesis of polyhydroxylated indolizidin