89945-90-4

Upstream product

• 16290-20-3 1,4-bis(2,4-dimethoxyphenyl)butane-1,4-dione 
• 2746-25-0 p-Methoxybenzyl bromide 
• 125304-89-4 2',4,4'-trimethoxydihydrochalcone trimethylsilyl enol ether 
• 77-78-1 dimethyl sulfate 
• 89945-88-0 brackenin 
• 93903-83-4 1-(2,4-dimethoxyphenyl)-3-(4-methoxyphenyl)propan-1-one 

Downstream Products

• 126525-64-2 2,5-Bis-(2,4-dimethoxy-phenyl)-3,4-bis-(4-methoxy-benzyl)-furan 

Relevant academic research and scientific papers

Synthesis of 1,4-bis-(2,4-dimethoxyphenyl)-2,3-bis-(4-methoxybenzyl)butane-1,4-dione

The synthesis of meso and racemic 1,4-bis-(2,4-dimethoxyphenyl)-2,3-bis-(4-methoxybenzyl)-butane-1,4-dione, a brackenin like molecule from commercially available 2,4-dimethoxybenzaldehyde is described.

Medicinal Plants of Southern Africa. Part 4. Synthesis of Brackenin-like Molecules from 1,4-Dicarbonyl Precursors and by Oxydative Coupling. X-Ray Molecular Structure of Racemic-2,3-Dibenzyl-1,4-diphenylbutane-1,4-dione

Oxidative coupling of appropriate trimethylsilyl enol ethers is shown to give 1,4-diaryl-1,4-diketones in acceptable yields.Subsequent dibenzylation of these intermediates affords compounds related to the naturally occuring brackenin (1).Examination of these products by 1H n.m.r. and 13C n.m.r. demonstrates that these techniques can be used for the determination of relative configurations without resorting to X-ray crystallography.

BRACKENIN, A DIMERIC DIHYDROCHALCONE FROM BRACKENRIDGEA ZANGUEBARICA

Brackenin, a new dimeric dihydrochalcone isolated from Brackenridgea zanguebarica, has been shown to consist of two dihydroisoliquiritigenin units joined by a carbon-to-carbon link between the two α-carbon atoms. - Key Word Index: Brackenridgea zanguebarica; Ochnaceae; bark; dimeric dihydrochalcone; dihydroisoliquiritigenin.