89951-60-0

Usage

Uses

Used in Pharmaceutical Industry:
[1,1'-Biphenyl]-3-carboxaldehyde, 2-methylis used as an intermediate in the synthesis of various pharmaceuticals. Its unique structure allows for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
[1,1'-Biphenyl]-3-carboxaldehyde, 2-methylis used in the production of agrochemicals, such as pesticides and herbicides. Its chemical properties make it suitable for the development of effective and targeted agricultural products.
Used in Organic Synthesis:
[1,1'-Biphenyl]-3-carboxaldehyde, 2-methylis used as a building block in various organic synthesis processes. Its versatility allows for the creation of a wide range of compounds with different properties and applications.

Upstream product

• 115363-11-6 2-methyl-[1,1’-biphenyl]-3-carboxylic acid 
• 7499-08-3 3-chloro-2-methylbenzoic acid 
• 98-80-6 phenylboronic acid 
• 76350-90-8 (2-methyl-[1,1′-biphenyl]-3-yl)methanol 
• 83647-40-9 3-bromo-2-methylbenzaldehyde 

Downstream Products

• 76350-90-8 (2-methyl-[1,1′-biphenyl]-3-yl)methanol 

Relevant academic research and scientific papers

Synthesis method of key intermediate of immune regulator

The method comprises the following steps: dissolving compound 2 and compound 3, adding potassium carbonate, replacing nitrogen and adding S-Phos liter reaction. After completion of the cooling, filtration, concentration and organic phase were washed and d

Microwave-assisted organic acid-base-co-catalyzed tandem Meinwald rearrangement and annulation of styrylepoxides

A novel organic acid-base-co-catalyzed conversion of styrylepoxides into [1,1′-biaryl]-3-carbaldehydes was realized under microwave irradiation. Styrylepoxides first underwent an acid-catalyzed Meinwald rearrangement followed by a tandem base-catalyzed Michael addition, aldol addition, and aromatization sequence to generate [1,1′-biaryl]-3-carbaldehydes.

HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS

Disclosed are compounds of Formula (I′), methods of using the compounds as immunomodulators, and pharmaceutical compositions comprising such compounds. The compounds inhibit PD-1/PD-L1 interaction and are useful in treating, preventing or ameliorating diseases or disorders such as cancer or infections.

HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS

Disclosed are compounds of Formula (I), methods of using the compounds as immunomodulators, and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders such as cancer or infections.

HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS

Disclosed are compounds of Formula (I), methods of using the compounds as immunomodulators, and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders such as cancer or