89973-67-1

Basic information

• Product Name: trans-PdCl₂(Gly-L-PheOEt)2
• CAS NO: 89973-67-1
• Molecular Weight: 677.921
• Mol File: 89973-67-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: trans-PdCl₂(Gly-L-PheOEt)2(CAS DataBase Reference)
• NIST Chemistry Reference: trans-PdCl₂(Gly-L-PheOEt)2(89973-67-1)
• EPA Substance Registry System: trans-PdCl₂(Gly-L-PheOEt)2(89973-67-1)

Safety Data

• Hazardous Substances Data: 89973-67-1(Hazardous Substances Data)

Upstream product

• 79351-56-7 trans-PdCl₂(GlyOH)2 
• 3081-24-1 H-Phe-OEt 
• 1892-57-5 N-(3-dimethylaminopropyl)-N-ethylcarbodiimide 

Relevant articles and documents

Metal Complexes with Biologically Important Ligands, XLIV. - Platinum(II) and Palladium(II) as Amino Protecting Groups. Metal Complexes with Silyl Esters and Acid Chlorides as Ligands and Peptide Synthesis at the Complex

The cleavage of the chelate ring of platinum(II) and palladium(II) glycinate, cis-, trans-M(NH2CH2COO)2 (M = Pt, Pd), by trialkylchlorosilanes results in the formation of the complexes cis-, trans-MCl2(NH2CH2CO2SiR3)2 (1).Treatment of 1 or of cis-, trans-MCl2(NH2CHRCO2H)2, respectively, with oxalyl chloride and DMF gives the α-amino acid chloride complexes cis-, trans-MCl2(NH2CHRCOCl)2 (2) from which - using N-(trimethylsilyl)-α-amino acid esters - a series of dipeptide complexes cis-, trans-MCl2(dipeptideOR)2 (R = H, alkyl, SiMe3) (3) has been obtained. trans-Palladium complexes of type 3 and of type cis-PdCl2(HisNHCHRCO2Et) (4) are also formed from the corresponding α-amino acid complexes and α-amino acid esters with a water-soluble carbodiimide.