899794-53-7

Upstream product

• 29568-66-9 2-phenyl-2-vinyl-[1,3]dioxolane 
• 93624-01-2 O-ethyl S-2-(4-methoxyphenyl)-2-oxoethyl carbonodithioate 
• 2632-13-5 2-Bromo-4'-methoxyacetophenone 
• 169053-08-1 2-Phenyl-2-[2-(toluene-4-sulfonyl)-ethyl]-[1,3]dioxolane 
• 52481-46-6 1-phenyl-3-tosylpropan-1-one 
• 936-59-4 3-chloropropiophenone 

Downstream Products

• 110719-03-4 1-(4-methoxyphenyl)-5-phenylpentane-1,5-dione 
• 33777-95-6 2-(4-methoxyphenyl)-6-phenylpyridine 
• 899794-56-0 1-(4-methoxyphenyl)-4-(2-phenyl[1,3]dioxolan-2-yl)butan-1-one 

Relevant academic research and scientific papers

An expedient, flexible and convergent access to selectively protected 1,5-dicarbonyl compounds. Applications to the synthesis of 2,6-disubstituted pyridines and thiopyridines

Intermolecular addition of 2-oxoalkyl radicals generated from the corresponding S-alkyl-O-ethyl dithiocarbonates on vinyl ketals afforded selectively protected 1,5-dicarbonyl compounds in good yields. These key-intermediates can be converted into a plethora of useful substances. Transformations to pyridines and thiopyridines were given as examples. Georg Thieme Verlag Stuttgart.