89989-62-8Relevant academic research and scientific papers
ALKYNYL PHOSPHINE GOLD COMPLEXES FOR TREATING BACTERIAL INFECTIONS
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Page/Page column 110; 111; 112; 113, (2017/08/01)
A compound of formula (I) for use in the prevention or treatment of a bacterial infection.
Preparative routes to the first tri- and tetra(alkynyl)gold(III) compounds: (L)Au(C=CR)3 and [ER4]_ [Au(C≡CR) 4]-
Schuster, Oliver,Schmidbaur, Hubert
, p. 2289 - 2296 (2008/10/09)
The preparation of tri(alkynyl)gold(III) complexes (RC≡C) 3Au(L) as metastable compounds was discussed. It was found that the complex can be prepared if a small and strong trialkylphosphine donor was introduced as an auxiliary ligand L. The complex with L = PMe3 was crystallize in a solvent-free form and as a 1:1 solvate with CH 2Cl2. The results show that the stability of polyalkynyl complexes of gold(III) centers appears to be generally lower than that of the isoelectronic platinum(II) centers.
Preparation, structure and decomposition of gold(I) and gold(III) acetylide complexes
Schuster, Oliver,Liau, Ruei-Yang,Schier, Annette,Schmidbaur, Hubert
, p. 1429 - 1441 (2008/10/09)
1-Alkynyl-dimethyl(triorganophosphine)gold(III) complexes of the type cis-Me2(Ph3P)Au-C≡C-R with R = H, Me, Ph (1-3) have been prepared from the cis-Me2(Ph3P)AuX (X = Cl, I) complexes and lithium alkynyls. The crystal structures of 1 and 2 have been determined together with those of the reference compounds cis-Me 2(Ph3P)AuX (X = Cl, I) and cis-Me2(Me 3P)AuI. The molecules have a standard square planar geometry and are not associated into oligomers. Due to the different hybridization of the carbon orbitals, the Au-C(≡CR) bonds are found significantly shorter than the Au-CH3 bonds. Compounds 1-3 are stable colourless, crystalline solids at 20°C but decompose on heating with selective (cis) reductive elimination of ethane and formation of the gold(I) alkynyls (Ph3P)Au-C≡C-R thus retaining the stronger gold-alkynyl bonds. Two complexes of this type have also been prepared by conventional routes from (R3P)AuX complexes and the crystal structures of (Me3P)Au-C≡C-Ph and [(p-Tol) 3P]Au-C≡C-H have been determined. The former with the small Me3P ligand is associated into two different trimers via aurophilic bonding and further aggregated into chains via weak inter-trimer contacts, while the latter is a monomer owing to the steric bulk of the (p-Tol)3P ligand.
SYNTHESE UND EIGENSCHAFTEN NEUER KUPFER- UND GOLD-KOMPLEXE DES TYPS C5H5MPR3, C5Me5MPR3 UND R"C2MPR3 (M=Cu, Au) SOWIE DIE KRISTALLSTRUKTUR VON C5H5AuPi-Pr3
Werner, H.,Otto, H.,Ngo-Khac, Tri,Burschka, Ch.
, p. 123 - 136 (2007/10/02)
The complexes C5H5CuPR3 (R=Me,i-Pr), C5H5AuPR3 (R=Me,i-Pr), C5Me5CuPR3(R=Me,i-Pr,Ph) and C5Me5AuPR3 (R=i-Pr,Ph) are prepared from n or ClAuPR3 and LiC5H5(TlC5H5) or LiC5Me5, respectively.According to the 1H and 13C NMR spectra, the cyclopentadien
Chemistry of the Group 1B Metals. XVII. Preparation of Some Gold(I) Acetylide Complexes Containing Group 5 Donor Ligands: Crystal and Molecular Structures of Au(C2C6F5)(PPh3)
Bruce, Michael I.,Horn, Ernst,Matisons, Janis G.,Snow, Michael R.
, p. 1163 - 1170 (2007/10/02)
Experimentally convenient syntheses of a series of gold(I) acetylide complexes containing tertiary phosphines include reactions between AuCl(PR3) and alk-1-ynes, either in diethylamine in the presence of copper(I) halides, or with methanol/sodium methoxide.Yields are good to excellent; several compounds are light-sensitive, and react violently with chlorinated solvents.The crystal structure of Au(C2H6F5)(PPh3) has been determined.It is monomeric, with almost linear two-coordinate Au: Au-C 1.993(14), Au-P 2.274(3), CC 1.197(16) Angstroem.Crystals are monoclinic, space group P21/c, with a 16.104(2), b 8.653(1), c 17.560(3) Angstroem, β 112.98(1) deg, Z 4; 1761 data with I > 2.5?(I) were refined to R, Rw = 0.033, 0.034.
