89998-53-8Relevant academic research and scientific papers
Thermal Rearrangement of Vinylallenes: Synthesis of 3-Deoxy-1α-hydroxy-14-epiprevitamin D3
Jeganathan, S.,Johnston, Allen D.,Kuenzel, Elizabeth A.,Norman, Anthony W.,Okamura, Willian H.
, p. 2152 - 2158 (2007/10/02)
The lithium salt of the terminal allene 12a was reacted with keto enol ether 13 to give the vinylallenones 8a(6R) and 9a(6S).On reduction with sodium borohydride, 8a afforded vinylallenols 8b(1R,6R) and 8c(1S,6R); similarly 9a gave 9b(1R,6S) and 9c(1S,6S)
ON THE LITHIUM DIMETHYLCUPRATE INDUCED CONVERSION OF PROPARGYLIC ESTERS INTO ALLENES USING A STEROIDAL C/D FRAGMENT DERIVED FROM VITAMIN D3 AS A STEREOCHEMICAL PROBE.
Haces, Alberto,Kruchten, Eugene M. G. A. van,Okamura, William H.
, p. 2707 - 2710 (2007/10/02)
The reactions of (CH3)2CuLi with various C-8 epimeric propargylic esters derived from Grundmann's ketone, a C/D steroid fragment originating from vitamin D3, lead to the corresponding allenes, the stereochemistry of which indicate a preferred a
