90-48-2

Basic information

• Product Name: 4-Chlorobiphenyl-2-amine
• Synonyms: 4-Chlorobiphenyl-2-amine
• CAS NO: 90-48-2
• Molecular Formula: C₁₂H₁₀ClN
• Molecular Weight: 203.67
• Mol File: 90-48-2.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-Chlorobiphenyl-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Chlorobiphenyl-2-amine(90-48-2)
• EPA Substance Registry System: 4-Chlorobiphenyl-2-amine(90-48-2)

Safety Data

• Hazardous Substances Data: 90-48-2(Hazardous Substances Data)

Upstream product

• 823-57-4 2-bromo-5-chloroaniline 
• 98-80-6 phenylboronic acid 

Downstream Products

• 94211-51-5 2-Benzamido-4-chlorbiphenyl 
• 20927-47-3 3-chlorophenanthridin-6(5H)-one 
• 2523-44-6 2-chloro-9H-fluorene 
• 98351-84-9 3-Chloro-6-(4-nitro-phenyl)-phenanthridine 
• 98351-87-2 3-chloro-6-(4′-methoxyphenyl)phenanthridine 
• 98351-81-6 3-chloro-6-(4′-chlorophenyl)phenanthridine 
• 94255-69-3 3-chloro-6-phenylphenanthridine 
• 76838-46-5 1-Benzoyl-3-(4-chloro-biphenyl-2-yl)-thiourea 
• 98351-97-4 (4-Chloro-biphenyl-2-yl)-[1-(4-methoxy-phenyl)-meth-(Z)-ylidene]-amine 
• 98351-89-4 (4-Chloro-biphenyl-2-yl)-[1-phenyl-meth-(Z)-ylidene]-amine 
• 98351-95-2 (4-Chloro-biphenyl-2-yl)-[1-(4-nitro-phenyl)-meth-(Z)-ylidene]-amine 
• 98351-92-9 (4-Chloro-biphenyl-2-yl)-[1-(4-chloro-phenyl)-meth-(Z)-ylidene]-amine 
• 188425-85-6 boscalid 

Relevant articles and documents

Additive-free radical cascade reaction of oxime esters: Synthesis of pyrroline-functionalized phenanthridines

A variety of dihydropyrrole-functionalized phenanthridines were efficiently synthesized by the metal-free, radical cascade cyclization reaction of 2-isocyanobiphenyls with γ,δ- unsaturated oxime esters. The C-N/C-C/C-C bonds were formed via the oil bath method in a one-pot procedure with broad substrate applicability. The radical process was supported by kinetic isotope effect studies and radical inhibition studies.

Rhodium(I)-Catalyzed Aryl C-H Carboxylation of 2-Arylanilines with CO2

An unprecedented Rh(I)-catalyzed, amino-group-assisted C-H carboxylation of 2-arylanilines with CO2 under redox-neutral conditions has been developed. This reaction was promoted by a phosphine ligand with t-BuOK as the base and did not require the use of additional strong organometallic reagent. It enabled an efficient direct conversion of a broad range of 2-(hetero)arylanilines including electron-deficient heteroarenes to various phenanthridinones. Possible intermediates of the reaction were also evaluated in the preliminary mechanistic studies.

Arylative cyclization of 2-isocyanobiphenyls with anilines: One-pot synthesis of 6-arylphenanthridines via competitive reaction pathways

A transition-metal-free method for the synthesis of C6 phenanthridine derivatives by arylative cyclization of 2-isocyanobiphenyls with arylamines in one pot was developed. Mechanistic studies suggest that electrophilic aromatic substitution (SEAr) of a nitrilium intermediate and homolytic aromatic substitution (HAS) of an imidoyl radical intermediate are two competitive reaction pathways involved in the annulation step.