900-94-7Relevant academic research and scientific papers
L'AZA-YLURE N-LITHIE (C6H5)3P=NLi, REACTIF D'AMINATION
Cristau, H. J.,Chiche, L.,Kadoura, J.,Torreilles, E.
, p. 3931 - 3934 (1988)
The preparation of the lithiated aza-ylide 3 has been improved and its one-pot reactivity toward alkyl and acyl halides to give amino-phosphonium salts and accordingly amines is described.
Alkylation et acylation de la triphenylphosphinimine N-lithiee
Cristau, Henri-Jean,Kadoura, Jumaah,Chiche, Laurent,Torreilles, Eliane
, p. 515 - 520 (2007/10/02)
A new synthetic approach to primary and secondary amines using N-lithiated triphenylphosphinimine is reported.This key reagent, accessible in two steps from dibromortiphenylphosphorane and ammonia, when treated with electrophiles yields N-substituted triphenylphosphinimine derivatives.These can react to give N-mono or disubstituted triphenylphosphonium salts which upon hydrolysis lead to the corresponding primary and secondary amines.
