90002-50-9

Basic information

• Product Name: 2-((2-aMino-4-broMophenyl)aMino)ethanol
• Synonyms: 2-((2-aMino-4-broMophenyl)aMino)ethanol;2-((2-AMINO-4-BROMOPHENYL)AMINO)ETHANOL(WXG00852)
• CAS NO: 90002-50-9
• Molecular Formula: C₈H₁₁BrN₂O
• Molecular Weight: 231.08974
• Mol File: 90002-50-9.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-((2-aMino-4-broMophenyl)aMino)ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-((2-aMino-4-broMophenyl)aMino)ethanol(90002-50-9)
• EPA Substance Registry System: 2-((2-aMino-4-broMophenyl)aMino)ethanol(90002-50-9)

Safety Data

• Hazardous Substances Data: 90002-50-9(Hazardous Substances Data)

Usage

Type of compound

Synthetic organic compound

Use

Pharmacological tool for studying adrenoceptors (particularly α1and α2-adrenoceptors)

Mechanism of action

Potent and selective α1B-adrenoceptor antagonist

Applications

Investigating function and pharmacology of adrenoceptors in various biological systems, potential therapeutic applications in the future

Importance

Valuable resource for studying adrenoceptor-mediated signaling pathways

Upstream product

• 364-73-8 4-Bromo-1-fluoro-2-nitrobenzene 
• 89980-83-6 2-(4-bromo-2-nitro-anilino)-ethanol 

Downstream Products

• 116465-66-8 2-(5-bromo-1H-benzimidazol-1-yl)ethanol 
• 1239879-61-8 tert-butyl 3-(5-bromo-2-(2-hydroxyethylamino)phenylamino)-3-oxopropylcarbamate 
• 1272321-55-7 2-(1-(tert-butoxycarbonyl)piperidin-2-yl)acetic acid 
• 1272321-50-2 (S)-tert-butyl 2-(2-(5-bromo-2-(2-hydroxyethylamino)phenylamino)-2-oxoethyl)pyrrolidine-1-carboxylate 
• 1272321-52-4 ⁽⁵⁾-tert-butyl 2-((5-bromo-1-(2-(tosyloxy)ethyl)-1H-benzo[d]imidazol-2-yl)methyl)pyrrolidine-1-carboxylate 
• 1272321-53-5 C₂₁H₂₄BrN₃O₃S 
• 1272320-71-4 (S)-4-(2,3,5,6,13,13a-hexahydro-1H-benzo[4,5]imidazo[1,2-d]pyrrolo[2,1-g][1,4]diazepin-10-yl)benzonitrile 
• 1382805-41-5 4-(benzyloxy)-1-(1,2,3,4-tetrahydropyrazino[1,2-a]benzimidazol-8-yl)pyridin-2(1H)-one 
• 1382805-19-7 tert-Butyl 8-(4-(benzyloxy)-2-oxopyridin-1(2H)-yl)-3,4-dihydropyrazino[1,2-a]benzimidazole-2(1H)-carboxylate 
• 1382805-14-2 tert-Butyl 2-(5-bromo-2-(2-hydroxyethylamino)phenylamino)-2-oxoethylcarbamate 

Relevant articles and documents

TETRAHYDRO-AZACARBOLINE MCH-1 ANTAGONISTS, METHODS OF MAKING, AND USES THEREOF

The present invention relates to tetrahydro-azacarboline derivatives of formula (I): having the substituents as described herein which are melanin-concentrating hormone (MCH-1) receptor antagonists. The present invention also relates to pharmaceutical com

HISTAMINE H3 INVERSE AGONISTS AND ANTAGONISTS AND METHODS OF USE THEREOF

Provided herein are fused imidazolyl compounds, methods of synthesis, and methods of use thereof. The compounds provided herein are useful for the treatment, prevention, and/or management of various disorders, such as neurological disorders and metabolic disorders. Compounds provided herein inhibit the activity of histamine H3 receptors and modulate the release of various neurotransmitters, such as histamine, acetylcholine, norepinephrine, and dopamine (e.g. at the synapse). Pharmaceutical formulations containing the compounds and their methods of use are also provided herein.