9002-10-2

Basic information

• Product Name: TYROSINASE
• Synonyms: tyrosinase from mushroom;Tyrosinase mushroom;TYROSINASE FROM MUSHROOM, LYOPH., >= 2000 UNITS/MG;PHENOLASE FROM POTATO;TyrosinaseExMushroom;exMushroom;AGARICUSBISPORUSTYROSINASE;Tyrosinase from mushroom,Catechol Oxidase, Monophenol Monooxygenase, Monophenol, dihydroxyphenylalanine:oxygen oxidoreductase, Polyphenol Oxidase
• CAS NO: 9002-10-2
• Molecular Formula: NULL
• EINECS: 232-653-4
• Mol File: 9002-10-2.mol
• Article Data: 0

Chemical Properties

• Melting Point: 89-94 °C
• Appearance: /lyophilized powder
• Storage Temp.: −20°C
• CAS DataBase Reference: TYROSINASE(CAS DataBase Reference)
• NIST Chemistry Reference: TYROSINASE(9002-10-2)
• EPA Substance Registry System: TYROSINASE(9002-10-2)

Safety Data

• Hazard Codes: Xn
• Statements: 42
• Safety Statements: 22-24/25-45
• WGK Germany: 2
• F: 10-21
• Hazardous Substances Data: 9002-10-2(Hazardous Substances Data)

Usage

Uses

Tyrosinase activity has been assessed in a study that developed an alternative therapeutic agent for treating hyperpigmentation. Tyrosinase has also been used in a study to investigate the oculocutaneous albinism phenotype in the Pakistani population.

General Description

Isoelectric point (pI): 4.7-5pH optimum is 6-7Molecular weight: 128 kDa by sedimentation velocity diffusion; 133?kDa by light-scattering measurements, and 119.5 kDa by electrophoresis.Tyrosinase is a copper-containing oxidase, which has activity for both catechols and cresol. It is responsible for browning reactions. The enzyme is reported to have two binding sites for aromatic substrates and a different binding site for oxygen-copper. The copper is probably Cu(I), with inactivation involving oxidation to Cu(II) ion.

Biochem/physiol Actions

Converts tyrosine to L-DOPA or tyramine to dopamine