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9002-13-5 Usage


Urease is an enzyme found in the natural environment, including water and soil, as well as in the human body, where it is associated with protein degradation. It is capable of urea hydrolysis, resulting in the production of ammonia and carbamate, which can lead to an increase in pH. Urease and the ammonia generated during urea hydrolysis may be toxic to human tissue and could play a role in long-lasting diseases such as atherosclerosis, urinary tract infections, or rheumatoid arthritis.


Used in Clinical Applications:
Urease is used as a clinical reagent for the determination of urea in body fluids.
Used in Environmental Analysis:
Urease from Canavalia ensiformis is used for urea determination in various samples, such as legumes, and may be useful for the detection of pathogens as well as heavy-metal ions.
Used in Agricultural Applications:
Urease, an enzyme, converts urea into ammonium carbonate [(NH4)2CO3] that releases ammonia, activating the hydrolysis of urea. This process can affect crop growth and soil health.
Used in Environmental Wastewater Treatment:
Urease can be used to analyze urea concentration in blood, urine, alcoholic beverages, natural water, and environmental wastewaters, as well as to analyze heavy metal content in natural waters, wastewaters, and soil.
Used in Special Cases:
Urease can be used to remove urea from artificial kidney dialyzates, alcohol beverages, and fertilizer wastewaters, control or shift pH for multi-enzyme reaction systems, hydrolyze urea as sources of ammonia or carbon dioxide, and for wastewater reclamation for life support systems in space.


[1] Iwona Konieczna, Paulina ?arnowiec, Marek Kwinkowski, Beata Kolesińska, Justyna Fr?czyk, Zbigniew Kamiński, Wies?aw Kaca (2012) Bacterial Urease and its Role in Long-Lasting Human Diseases, Curr Protein Petp Sci., 13, 789-806 [2] Yingjie Qin, Joaquim M. S. Cabral (2002) Review: Properties and Applications of Urease, Biocatalysis and Biotransformation, 20, 1-14

Biochem/physiol Actions

Urease catalyzes the hydrolysis of urea into carbon dioxide and ammonia. Urease is involved in nitrogen metabolism and urea degradation. Urease from Canavalia ensiformis binds 2 nickel ions per subunit .

Check Digit Verification of cas no

The CAS Registry Mumber 9002-13-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 9,0,0 and 2 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 9002-13:
65 % 10 = 5
So 9002-13-5 is a valid CAS Registry Number.



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017


1.1 GHS Product identifier

Product name Urease

1.2 Other means of identification

Product number -
Other names CLEC-urease

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:9002-13-5 SDS

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