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9002-13-5

Basic Information
CAS No.: 9002-13-5
Name: Urease
Molecular Structure:
Molecular Structure of 9002-13-5 (Urease)
Formula: Unspecified
Molecular Weight: 30.06900
Synonyms: Urease LF;E.C.3.5.1.5;Urea amidohydrolase;Enzyme urease;Jack bean urease;Urease enzyme preparation from Lactobacillus fermentum;
EINECS: 232-656-0
Solubility: It is slightly soluble in water.
Appearance: yellow powder
Hazard Symbols: HarmfulXn
Risk Codes: 36/37/38-42
Safety: 22-24-26-36/37-45-36-23
PSA: 0.00000
LogP: 0.00000
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    9002-13-5

    Urease(jack bean)

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  • Urease 9002-13-5

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  • Urease 9002-13-5

  • Casno:

    9002-13-5

    Urease 9002-13-5

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  • Urease

  • Casno:

    9002-13-5

    Urease

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Consensus Reports

Reported in EPA TSCA Inventory.

Specification

The Urease with CAS registry number of 9002-13-5 is also known as Enzyme urease and Urea amidohydrolase. The systematic name and product name are the same. It belongs to product categories of Biochemistry; Enzyme; Hydrolase; Metabolomics; 3.5.x.x Acting on C-N other than peptides; Diagnostic and Analytical EnzymesMetabolomics; General Metabolic Enzymes I-ZEnzyme Class Index; 3.x.x.x Hydrolases; Application Index; Enzymes, Inhibitors, and Substrates; General Metabolic Enzymes; Diagnostic and Analytical EnzymesResearch Essentials; EnzymesMetabolomics; Core Bioreagents. Its EINECS registry number is 232-656-0. This chemical is a white fine crystalline powder and should be stored in sealed containers in cool and dry place at 2-8 °C.

Preparation of Urease: the raw material is con powder, which is extracted with acetone, filtrated,centrifugated and crystallizated to obtain the product.

Uses of Urease: it can be used for biochemical research, such as decomposing urea in the remaining wine and inhibiting the formation of ethyl carbamate. This chemical is often used in clinical as diagnostic enzyme for the determination of blood and urine urea urease. It also can be used to prevent hepatic coma.

When you are using this chemical, please be cautious about it. As a chemical, it is irritating to eyes, respiratory system and skin and may cause sensitisation by inhalation. During using it, wear suitable protective clothing and gloves. Besides, do not breathe gas/fumes/vapour/spray and avoid contact with skin. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. If you feel unwell seek or accident happens medical advice immediately.

The toxicity data is as follows:
 

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 intraperitoneal 35mg/kg (35mg/kg) SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

BEHAVIORAL: SLEEP

KIDNEY, URETER, AND BLADDER: URINE VOLUME INCREASED
American Journal of Physiology. Vol. 206, Pg. 731, 1964.
mouse LD50 intraperitoneal 50mg/kg (50mg/kg) SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

BEHAVIORAL: SLEEP

KIDNEY, URETER, AND BLADDER: URINE VOLUME INCREASED
American Journal of Physiology. Vol. 206, Pg. 731, 1964.
mouse LD50 subcutaneous 58mg/kg (58mg/kg)   American Journal of Physiology. Vol. 206, Pg. 731, 1964.
rabbit LD50 intraperitoneal 25mg/kg (25mg/kg) SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

BEHAVIORAL: SLEEP

KIDNEY, URETER, AND BLADDER: URINE VOLUME INCREASED
American Journal of Physiology. Vol. 206, Pg. 731, 1964.
rabbit LD50 intravenous 6mg/kg (6mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
American Journal of Physiology. Vol. 206, Pg. 731, 1964.
rat LD50 intraperitoneal 48mg/kg (48mg/kg) SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

BEHAVIORAL: SLEEP

KIDNEY, URETER, AND BLADDER: URINE VOLUME INCREASED
American Journal of Physiology. Vol. 206, Pg. 731, 1964.
rat LD50 intravenous 20mg/kg (20mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
American Journal of Physiology. Vol. 206, Pg. 731, 1964.