9002-92-0

Basic information

• Product Name: Polyoxyethylene lauryl ether
• Synonyms: Brij|r L23;BRIJ 35 FOR SYNTHESIS;Polyoxyethylene(23)lauryl ether, 30% w/v solution in H2O;Brij[R] L4;Brij L23;Poly(oxy-1,2-ethanediyl),a-dodecyl-w-hydroxy-;Brij-35, 20% Solution;Macrogol lauryl ether
• CAS NO: 9002-92-0
• Molecular Formula: C58H118O24
• Molecular Weight: 1199.55
• EINECS: 500-002-6
• Product Categories: Ether Type (Surfactants);Ethylene Glycols & Monofunctional Ethylene Glycols;Functional Materials;Monofunctional Ethylene Glycols;Nonionic Surfactants;Surfactants;Biochemistry;Nonionic Surfactants (for Biochemistry);Surfactants (for Biochemistry);Detergents for Cell Lysis;DetergentsNative Protein Sample Preparation;Cell Lysis and Protein Extraction Reagents;Core Bioreagents;Research Essentials
• Mol File: 9002-92-0.mol
• Article Data: 0

Chemical Properties

• Melting Point: 41-45 °C(lit.)
• Boiling Point: 100 °C(lit.)
• Flash Point: >230 °F
• Appearance: White/Waxy Pellets
• Density: 0.99 g/mL±0.002 g/mL at 20 °C
• Vapor Pressure: <1 mm Hg ( 20 °C)
• Refractive Index: n20/D 1.461
• Storage Temp.: Store at RT.
• Solubility: H2O: 40 mg/mL at 20 °C, clear, colorless
• PKA: 0[at 20 ℃]
• Water Solubility: soluble
• Stability: Stable. Combustible. Incompatible with strong oxidizing agents.
• Merck: 14,7558
• CAS DataBase Reference: Polyoxyethylene lauryl ether(CAS DataBase Reference)
• NIST Chemistry Reference: Polyoxyethylene lauryl ether(9002-92-0)
• EPA Substance Registry System: Polyoxyethylene lauryl ether(9002-92-0)

Safety Data

• Hazard Codes: Xn,Xi
• Statements: 22-41-36/37/38-38-37/38-36
• Safety Statements: 26-39-37/39-36/37/39-36-24/25
• RIDADR: UN 3082 9/PG 3
• WGK Germany: 3
• RTECS: MD0875000
• F: 3
• TSCA: Yes
• Hazardous Substances Data: 9002-92-0(Hazardous Substances Data)

Usage

Description

As a non-ionic surfactant, polyoxyethylene lauryl ether has excellent washing, emulsifying, dispersing, wetting, and solubilizing functions. It also shows strong foaming ability, easy rinsing performance, and excellent detergency. Because this substance acts as one of the lowest irritant species among various surfactants, it is often selected as raw material for mild detergents, shampoos (such as baby shampoos), bath lotion, cleansing milk, and cosmetics. In addition, this chemical may function as emulsifier, softener, wetting agent, and foaming agent. In terms of solubilizing function, this product has been demonstrated to assist in solubilization of steroid hormones, benzoic acid derivatives, and barbiturates.1-3 Besides, when used as surfactant emulsifier, polyoxyethylene lauryl ether is proved to be an active agent for preparing nanoemulsions for food applications.4

Reference

Tomida, H.; Yotsuyanagi, T.; Ikeda, K., SOLUBILIZATION OF STEROID-HORMONES BY POLYOXYETHYLENE LAURYL ETHER. Chem. Pharm. Bull. 1978, 26, 2832-2837. Tomida, H.; Yotsuyanagi, T.; Ikeda, K., SOLUBILIZATION OF BENZOIC-ACID DERIVATIVES BY POLYOXYETHYLENE LAURYL ETHER. Chem. Pharm. Bull. 1978, 26, 2824-2831. Ikeda, K.; Kato, K.; Tukamoto, T., SOLUBILIZATION OF BARBITURATES BY POLYOXYETHYLENE LAURYL ETHER. Chem. Pharm. Bull. 1971, 19, 2510-+. Silva, H. D.; Cerqueira, M. A.; Vicente, A. A., Nanoemulsions for Food Applications: Development and Characterization. Food Bioprocess Technol. 2012, 5, 854-867.

Chemical Properties

White or almost white, unctuous and hygroscopic mass, melting at 24 °C into a colourless or yellowish, viscous liquid.

Uses

Different sources of media describe the Uses of 9002-92-0 differently. You can refer to the following data:
1. Brij L23 is a a pharmaceutical compound used in the schlerotherapy treatments, in those suffering from blood vessel malformations and mutations.
2. Solvent; nonionic emulsifier; pharmaceutic aid (surfactant); spermaticide.
3. Ethosperse(R) LA-4 is a medium range HLB, ethoxylated, nonionic ether of lauryl alcohol with broad range pH stability. It is suggested for use as an emulsifier in cosmetics to add body and texture (humectant), in household products and in lubricants.

Brand name

Brij 30 (ICI Americas).

General Description

Clear colorless to light yellow viscous liquid. Colorless at 266°F; brown at 644°F. Bland odor.

Air & Water Reactions

Water soluble.

Reactivity Profile

Polyoxyethylene lauryl ether is incompatible with strong oxidizing agents and strong bases.

Fire Hazard

Polyoxyethylene lauryl ether is combustible.

Flammability and Explosibility

Notclassified

Biochem/physiol Actions

Brij? L23 also referred to as Brij 35 or Polyoxyethylene (23) lauryl ether is a non-ionic detergent that lowers the non-specific protein adsorption and reduces electroosmotic pumping drastically. This allows the pH to be varied without adversely affecting the flow rate. It also used as a nonionic surfactant that decreases the absorbance of the blank, inhibits turbidity as well as provides linearity.

InChI:InChI=1/C58H118O24/c1-2-3-4-5-6-7-8-9-10-11-13-60-15-17-62-19-21-64-23-25-66-27-29-68-31-33-70-35-37-72-39-41-74-43-45-76-47-49-78-51-53-80-55-57-82-58-56-81-54-52-79-50-48-77-46-44-75-42-40-73-38-36-71-34-32-69-30-28-67-26-24-65-22-20-63-18-16-61-14-12-59/h59H,2-58H2,1H3