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Detomidine hydrochloride is an α-Adrenoceptor agonist that exhibits sedative and analgesic properties. It is a pharmaceutical compound known for its ability to induce a calm and sedated state in animals, as well as provide pain relief through the activation of α2 catecholamine receptors.
Used in Veterinary Medicine:
Detomidine hydrochloride is used as a sedative and analgesic agent for the management of anxiety, pain, and stress in animals. Its application in this industry is crucial for ensuring the well-being and comfort of animals during medical procedures, transportation, and handling.
Used in Equine Industry:
In the equine industry, Detomidine hydrochloride is used as a sedative to calm and manage horses during veterinary examinations, minor surgical procedures, and transportation. Its analgesic effects also help in reducing pain and discomfort associated with certain conditions or treatments.
Used in Small Animal Practice:
Detomidine hydrochloride is used in small animal practice as a sedative and analgesic for pets such as dogs and cats. It is particularly useful in situations where animals need to be calmed down or experience pain due to injuries or medical conditions.
Used in Wildlife and Zoo Animals:
Detomidine hydrochloride is also used in the management of wildlife and zoo animals, where it serves as a sedative and analgesic to facilitate safe handling, transportation, and medical interventions for a variety of species.
Overall, Detomidine hydrochloride is a valuable compound in the fields of veterinary medicine, equine industry, small animal practice, and wildlife management, providing essential sedative and analgesic effects for the welfare and comfort of animals.

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  • 90038-01-0 Structure
  • Basic information

    1. Product Name: Detomidine hydrochloride
    2. Synonyms: 5-[(2,3-DiMethylphenyl)Methyl]-1H-iMidazole Hydrochloride;DoMosedan;DorMosedan;MPV 253AII;DetoMidine hydrochloride (DorMosedan);API017;DTMT.HCl;1H-IMidazole,5-[(2,3-diMethylphenyl)Methyl]-, hydrochloride (1:1)
    3. CAS NO:90038-01-0
    4. Molecular Formula: C12H15ClN2
    5. Molecular Weight: 222.7139
    6. EINECS: N/A
    7. Product Categories: Inhibitors;APIs;API;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
    8. Mol File: 90038-01-0.mol
  • Chemical Properties

    1. Melting Point: 160°C
    2. Boiling Point: 386.5 °C at 760 mmHg
    3. Flash Point: 200.6 °C
    4. Appearance: /
    5. Density: N/A
    6. Vapor Pressure: 7.83E-06mmHg at 25°C
    7. Refractive Index: N/A
    8. Storage Temp.: Sealed in dry,Room Temperature
    9. Solubility: DMSO (Slightly), Methanol (Slightly)
    10. CAS DataBase Reference: Detomidine hydrochloride(CAS DataBase Reference)
    11. NIST Chemistry Reference: Detomidine hydrochloride(90038-01-0)
    12. EPA Substance Registry System: Detomidine hydrochloride(90038-01-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. RIDADR: UN 2811 6.1 / PGIII
    5. WGK Germany:
    6. RTECS: NI5160000
    7. HazardClass: N/A
    8. PackingGroup: N/A
    9. Hazardous Substances Data: 90038-01-0(Hazardous Substances Data)

90038-01-0 Usage

Biological Activity

detomidine hydrochloride produce dose-dependent sedative and analgesic effects, is a nonnarcotic, synthetic α2-adrenergic agonist

Veterinary Drugs and Treatments

At present, detomidine is only approved for use as a sedative analgesic in horses, but it has been used clinically in other species.

Check Digit Verification of cas no

The CAS Registry Mumber 90038-01-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,0,0,3 and 8 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 90038-01:
(7*9)+(6*0)+(5*0)+(4*3)+(3*8)+(2*0)+(1*1)=100
100 % 10 = 0
So 90038-01-0 is a valid CAS Registry Number.
InChI:InChI=1/C12H14N2.ClH/c1-9-4-3-5-11(10(9)2)6-12-7-13-8-14-12;/h3-5,7-8H,6H2,1-2H3,(H,13,14);1H

90038-01-0 Well-known Company Product Price

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  • TCI America

  • (D4331)  Detomidine Hydrochloride  >98.0%(HPLC)(T)

  • 90038-01-0

  • 200mg

  • 990.00CNY

  • Detail
  • Sigma-Aldrich

  • (Y0000001)  Detomidine hydrochloride  European Pharmacopoeia (EP) Reference Standard

  • 90038-01-0

  • Y0000001

  • 1,880.19CNY

  • Detail

90038-01-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name Detomidine Hydrochloride

1.2 Other means of identification

Product number -
Other names 5-[(2,3-dimethylphenyl)methyl]-1H-imidazole,hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:90038-01-0 SDS

90038-01-0Downstream Products

90038-01-0Relevant articles and documents

DETOMIDINE HYDROCHLORIDE CRYSTALLIZATION METHOD

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Page/Page column 4-5, (2008/06/13)

The present invention provides a method of isolating detomidine (I) hydrochloride as a crystalline salt. The method comprises hydrogenation under catalyst of compound of formula (II) in aqueous solution comprising hydrochloric acid, concentrating the solu

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