90044-00-1Relevant articles and documents
Synthesis of Halogenated Pyridines via the CuCl-Catalyzed Addition of Polyhaloacetonitriles to Olefins
Pews, R. Garth,Lysenko, Zenon
, p. 5115 - 5119 (1985)
Halogenated acetonitriles add smoothly to acrolein, methacrolein, and methacrolein dimethyl acetal in the presence of a catalytic amount of CuCl and triphenylphosphine, tri-n-butylphosphine, or triethylamine to give halogenated difunctional adducts.The adducts have been cyclized in high yields under acidic conditions to halogenated pyridines.