90044-18-1

Basic information

• Product Name: 1H-Pyrrolo(2,3-d)pyrimidine-5-carbonitrile, 4-methoxy-2-((4-O-(4-O-met hyl-beta-D-glucopyranosyl)-beta-D-glucopyranosyl)amino)-
• Synonyms: 1H-Pyrrolo(2,3-d)pyrimidine-5-carbonitrile, 4-methoxy-2-((4-O-(4-O-met hyl-beta-D-glucopyranosyl)-beta-D-glucopyranosyl)amino)-;dapiramicin B;4-Methoxy-2-[[4-O-(4-O-methyl-β-D-glucopyranosyl)-β-D-glucopyranosyl]amino]-1H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile
• CAS NO: 90044-18-1
• Molecular Formula: C21H29 N5 O11
• Molecular Weight: 0
• Mol File: 90044-18-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 914°Cat760mmHg
• Flash Point: 506.6°C
• Appearance: /
• Density: 1.66g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.685
• CAS DataBase Reference: 1H-Pyrrolo(2,3-d)pyrimidine-5-carbonitrile, 4-methoxy-2-((4-O-(4-O-met hyl-beta-D-glucopyranosyl)-beta-D-glucopyranosyl)amino)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrolo(2,3-d)pyrimidine-5-carbonitrile, 4-methoxy-2-((4-O-(4-O-met hyl-beta-D-glucopyranosyl)-beta-D-glucopyranosyl)amino)-(90044-18-1)
• EPA Substance Registry System: 1H-Pyrrolo(2,3-d)pyrimidine-5-carbonitrile, 4-methoxy-2-((4-O-(4-O-met hyl-beta-D-glucopyranosyl)-beta-D-glucopyranosyl)amino)-(90044-18-1)

Safety Data

• Hazardous Substances Data: 90044-18-1(Hazardous Substances Data)

Usage

Molecular structure

Pyrrolopyrimidine core with multiple glycosidic attachments.

Nitrile derivative

Contains a carbonitrile group (C≡N).

Methoxy group

Contains a -OCH3 group, which is an electron-donating group.

Glucosidic components

Contains two glucose moieties (beta-D-glucopyranosyl), which may have potential roles in carbohydrate metabolism or as a substrate for enzymatic processes.

Potential applications

Pharmaceutical research and drug development due to its unique structure, which may impart specific biological activities or interactions with cellular pathways.

Bioactivity

Further study and characterization may reveal novel therapeutic or bioactive properties.

InChI:InChI=1/C21H29N5O11/c1-33-15-8(5-27)36-20(14(32)12(15)30)37-16-9(6-28)35-19(13(31)11(16)29)26-21-24-17-10(18(25-21)34-2)7(3-22)4-23-17/h4,8-9,11-16,19-20,27-32H,5-6H2,1-2H3,(H2,23,24,25,26)/t8-,9-,11-,12-,13-,14-,15-,16-,19-,20+/m1/s1

Upstream product

• 69205-79-4 2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile 
• 908845-55-6 2-bromo-4-methoxy-7-(2-trimethylsilanyl-ethoxymethyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile 
• 908845-63-6 C₇₅H₉₁N₅O₁₈Si 
• 908845-62-5 2-amino-4-methoxy-7-(2-trimethylsilanyl-ethoxymethyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile 
• 908845-60-3 2-amino-4-oxo-7-(2-trimethylsilanyl-ethoxymethyl)-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile 
• 908845-58-9 (2R,3R,4S,5R,6S)-6-[(2R,3R,4S,5R,6R)-6-Azido-4,5-bis-(4-methoxy-benzyloxy)-2-(4-methoxy-benzyloxymethyl)-tetrahydro-pyran-3-yloxy]-4,5-bis-(4-methoxy-benzyloxy)-2-(4-methoxy-benzyloxymethyl)-tetrahydro-pyran-3-ol 
• 908845-57-8 (2R,4aR,6S,7R,8S,8aR)-6-[(2R,3R,4S,5R,6R)-6-Azido-4,5-bis-(4-methoxy-benzyloxy)-2-(4-methoxy-benzyloxymethyl)-tetrahydro-pyran-3-yloxy]-7,8-bis-(4-methoxy-benzyloxy)-2-(4-methoxy-phenyl)-hexahydro-pyrano[3,2-d][1,3]dioxine 
• 908845-54-5 (2R,3R,4S,5R,6R)-3,4-Bis-(4-methoxy-benzyloxy)-6-(4-methoxy-benzyloxymethyl)-5-[(2S,3R,4S,5R,6R)-5-methoxy-3,4-bis-(4-methoxy-benzyloxy)-6-(4-methoxy-benzyloxymethyl)-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-2-ylamine 
• 908845-59-0 C₆₁H₇₁N₃O₁₆ 

Relevant articles and documents

Total synthesis of dapiramicin B

The first total synthesis of dapiramicin B, a nucleoside antibiotic, is described. The characteristic N-glycoside linkage in dapiramicin B was effectively constructed by way of the Pd-catalyzed coupling reaction of a heptopyranosylamine with a bromopyrrol