900512-31-4Relevant academic research and scientific papers
Triazole oxytocin antagonists: Identification of an aryloxyazetidine replacement for a biaryl substituent
Brown, Alan,Brown, T. Bruce,Calabrese, Andrew,Ellis, Dave,Puhalo, Nicholas,Ralph, Michael,Watson, Lesa
scheme or table, p. 516 - 520 (2010/04/05)
A series of aryloxyazetidines, aryloxypyrrolidines and aryloxypiperidines were designed based on structural overlap with previously reported arylpyrazine Oxytocin antagonists. Similarly high levels of Oxytocin antagonism were achievable in these new serie
A convenient synthesis of highly substituted 3-N,N-dialkylamino-1,2,4- triazoles
Batchelor, David V.,Beal, David M.,Brown, T. Bruce,Ellis, David,Gordon, David W.,Johnson, Patrick S.,Mason, Helen J.,Ralph, Michael J.,Underwood, Toby J.,Wheeler, Simon
scheme or table, p. 2421 - 2424 (2009/04/08)
The title compounds are prepared from S-methylisothioureas and acyl hydrazides in moderate to good yields. The reaction is characterized by relatively mild conditions and very broad functional group tolerance. Georg Thieme Verlag Stuttgart.
